Hedgehog signaling in animal development: paradigms and principles PW Ingham, AP McMahon Genes & development 15 (23), 3059-3087, 2001 | 3732 | 2001 |
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity Y Echelard, DJ Epstein, B St-Jacques, L Shen, J Mohler, JA McMahon, ... Cell 75 (7), 1417-1430, 1993 | 2783 | 1993 |
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation B St-Jacques, M Hammerschmidt, AP McMahon Genes & development 13 (16), 2072-2086, 1999 | 2124 | 1999 |
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain AP McMahon, A Bradley Cell 62 (6), 1073-1085, 1990 | 1901 | 1990 |
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation DA Glass, P Bialek, JD Ahn, M Starbuck, MS Patel, H Clevers, MM Taketo, ... Developmental cell 8 (5), 751-764, 2005 | 1812 | 2005 |
HedgehogandBmpGenes are coexpressed at many diverse sites of cell–cell interaction in the mouse embryo MJ Bitgood, AP McMahon Developmental biology 172 (1), 126-138, 1995 | 1739 | 1995 |
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis Y Chai, X Jiang, Y Ito, P Bringas Jr, J Han, DH Rowitch, P Soriano, ... Development 127 (8), 1671-1679, 2000 | 1688 | 2000 |
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis BD Humphreys, SL Lin, A Kobayashi, TE Hudson, BT Nowlin, ... The American journal of pathology 176 (1), 85-97, 2010 | 1616 | 2010 |
Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse S Hayashi, AP McMahon Developmental biology 244 (2), 305-318, 2002 | 1608 | 2002 |
Female development in mammals is regulated by Wnt-4 signalling S Vainio, M Heikkilä, A Kispert, N Chin, AP McMahon Nature 397 (6718), 405-409, 1999 | 1534 | 1999 |
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase PS Danielian, D Muccino, DH Rowitch, SK Michael, AP McMahon Current biology 8 (24), 1323-1326, 1998 | 1440 | 1998 |
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice AM Clement, MD Nguyen, EA Roberts, ML Garcia, S Boillee, M Rule, ... science 302 (5642), 113-117, 2003 | 1404 | 2003 |
Fate of the mammalian cardiac neural crest X Jiang, DH Rowitch, P Soriano, AP McMahon, HM Sucov Development 127 (8), 1607-1616, 2000 | 1313 | 2000 |
Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development V Brault, R Moore, S Kutsch, M Ishibashi, DH Rowitch, AP McMahon, ... Development 128 (8), 1253-1264, 2001 | 1266 | 2001 |
Derivation of embryonic stem-cell lines from human blastocysts CA Cowan, I Klimanskaya, J McMahon, J Atienza, J Witmyer, JP Zucker, ... New England Journal of Medicine 350 (13), 1353-1356, 2004 | 1257 | 2004 |
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 K Stark, S Vainio, G Vassileva, AP McMahon Nature 372 (6507), 679-683, 1994 | 1256 | 1994 |
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo TP Yamaguchi, A Bradley, AP McMahon, S Jones Development 126 (6), 1211-1223, 1999 | 1178 | 1999 |
Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors SJ Rodda, AP McMahon Oxford University Press for The Company of Biologists Limited 133 (16), 3231 …, 2006 | 1141 | 2006 |
1 Developmental roles and clinical significance of Hedgehog signaling AP McMahon, PW Ingham, CJ Tabin Academic Press 53, 1-114, 2003 | 1128 | 2003 |
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities BD Harfe, PJ Scherz, S Nissim, H Tian, AP McMahon, CJ Tabin Cell 118 (4), 517-528, 2004 | 1085 | 2004 |