Zhen Yan
Zhen Yan
Professor and Director, Center for Exercise Medicine Research at Fralin Biomedical Research
Verified email at - Homepage
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway
T Akimoto, SC Pohnert, P Li, M Zhang, C Gumbs, PB Rosenberg, ...
Journal of Biological Chemistry 280 (20), 19587-19593, 2005
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy
JL Ruas, JP White, RR Rao, S Kleiner, KT Brannan, BC Harrison, ...
Cell 151 (6), 1319-1331, 2012
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
C Handschin, S Chin, P Li, F Liu, E Maratos-Flier, NK LeBrasseur, Z Yan, ...
Journal of Biological Chemistry 282 (41), 30014-30021, 2007
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7
JF Chen, Y Tao, J Li, Z Deng, Z Yan, X Xiao, DZ Wang
Journal of Cell Biology 190 (5), 867-879, 2010
Peroxisome proliferator-activated receptor-γ co-activator 1α-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced …
TR Koves, P Li, J An, T Akimoto, D Slentz, O Ilkayeva, GL Dohm, Z Yan, ...
Journal of Biological Chemistry 280 (39), 33588-33598, 2005
Structural modulation of gut microbiota in life-long calorie-restricted mice
C Zhang, S Li, L Yang, P Huang, W Li, S Wang, G Zhao, M Zhang, X Pang, ...
Nature communications 4 (1), 2163, 2013
PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity
VA Lira, CR Benton, Z Yan, A Bonen
American Journal of Physiology-Endocrinology and Metabolism 299 (2), E145-E161, 2010
Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance
VA Lira, M Okutsu, M Zhang, NP Greene, RC Laker, DS Breen, KL Hoehn, ...
The FASEB Journal 27 (10), 4184, 2013
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
G Leone, J DeGregori, Z Yan, L Jakoi, S Ishida, RS Williams, JR Nevins
Genes & development 12 (14), 2120-2130, 1998
Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle
Z Yan, M Okutsu, YN Akhtar, VA Lira
Journal of applied physiology 110 (1), 264-274, 2011
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
RC Laker, JC Drake, RJ Wilson, VA Lira, BM Lewellen, KA Ryall, ...
Nature communications 8 (1), 548, 2017
Exercise training-induced regulation of mitochondrial quality
Z Yan, VA Lira, NP Greene
Exercise and sport sciences reviews 40 (3), 159-164, 2012
Molecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle
JC Drake, RJ Wilson, Z Yan
The FASEB Journal 30 (1), 13, 2016
PGC-1α plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle
T Geng, P Li, M Okutsu, X Yin, J Kwek, M Zhang, Z Yan
American Journal of Physiology-Cell Physiology 298 (3), C572-C579, 2010
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells
Z Yan, J DeGregori, R Shohet, G Leone, B Stillman, JR Nevins, ...
Proceedings of the National Academy of Sciences 95 (7), 3603-3608, 1998
Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction
C Perrino, SVN Prasad, L Mao, T Noma, Z Yan, HS Kim, O Smithies, ...
The Journal of clinical investigation 116 (6), 1547-1560, 2006
p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting
JM McClung, AR Judge, SK Powers, Z Yan
American Journal of Physiology-Cell Physiology 298 (3), C542-C549, 2010
Highly coordinated gene regulation in mouse skeletal muscle regeneration
Z Yan, S Choi, X Liu, M Zhang, JJ Schageman, SY Lee, R Hart, L Lin, ...
Journal of Biological Chemistry 278 (10), 8826-8836, 2003
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
C Zechner, L Lai, JF Zechner, T Geng, Z Yan, JW Rumsey, D Collia, ...
Cell metabolism 12 (6), 633-642, 2010
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