| Compounds F Narjes, RI OLSSON, S Von Berg, S LEVER US Patent App. 10/011,566, 2018 | 346* | 2018 |
| Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease F Jeppsson, S Eketjäll, J Janson, S Karlström, S Gustavsson, LL Olsson, ... Journal of Biological Chemistry 287 (49), 41245-41257, 2012 | 163 | 2012 |
| Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer’s disease: design, synthesis, and characterization of pyrazines S Berg, M Bergh, S Hellberg, K Högdin, Y Lo-Alfredsson, P Söderman, ... Journal of medicinal chemistry 55 (21), 9107-9119, 2012 | 150 | 2012 |
| Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides BM Swahn, K Kolmodin, S Karlström, S von Berg, P Söderman, ... Journal of medicinal chemistry 55 (21), 9346-9361, 2012 | 95 | 2012 |
| New aminoimidazoles as β-secretase (BACE-1) inhibitors showing amyloid-β (Aβ) lowering in brain Y Gravenfors, J Viklund, J Blid, T Ginman, S Karlström, J Kihlström, ... Journal of medicinal chemistry 55 (21), 9297-9311, 2012 | 76 | 2012 |
| Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ RI Olsson, Y Xue, S von Berg, A Aagaard, J McPheat, EL Hansson, ... ChemMedChem 11 (2), 207-216, 2016 | 63 | 2016 |
| Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy BM Swahn, J Holenz, J Kihlström, K Kolmodin, J Lindström, N Plobeck, ... Bioorganic & medicinal chemistry letters 22 (5), 1854-1859, 2012 | 57 | 2012 |
| Iron-mediated allylic substitution reactions with chirality transfer. Stereochemistry of the formation of diastereo-and enantiomerically enriched olefinic and allylic … D Enders, B Jandeleit, S von Berg, G Raabe, J Runsink Organometallics 20 (21), 4312-4332, 2001 | 37 | 2001 |
| Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ... Journal of medicinal chemistry 61 (17), 7796-7813, 2018 | 33 | 2018 |
| Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production K Stroemberg, S Eketjaell, B Georgievska, K Tunblad, K Eliason, F Olsson, ... FEBS Journal 282 (1), 65-73, 2015 | 25 | 2015 |
| Diethyl [(phenylsulfonyl) methyl] phosphonate D Enders, S Von Berg, B Jandeleit Organic syntheses, 169-169, 2002 | 25 | 2002 |
| Synthesis of highly enantioenriched compounds via iron mediated allylic substitutions D Enders, B Jandeleit, S von Berg Synlett 1997 (Sup. I), 421-431, 1997 | 25 | 1997 |
| Compounds and their use as BACE inhibitors SVB Gabor Csjernyik, Sofia Karlstrom, Annika Kers, Karin Kolmodin, Martin ... US Patent US8,415,483, 2013 | 24* | 2013 |
| New compounds 575 J Holenz, S Karlstrom, J Kihlstrom, K Kolmodin, L Rakos, P Soderman, ... US Patent App. 12/618,114, 2009 | 23 | 2009 |
| Novel 8-sulfonylamino-3 aminosubstituted chroman or tetrahydronaphtalene derivatives modulating the 5ht6 receptor C Chu, A Lister, G Nordvall, C Petersson, D Rotticci, D Sohn, S Von Berg US Patent App. 11/915,173, 2006 | 19 | 2006 |
| Iron-Mediated Allylic Substitutions with Complete Chirality Transfer. Synthesis of Functionalized γ-Substituted Alkenylsulfones of High Enantiomeric Purity D Enders, S von Berg, B Jandeleit Synlett 1996 (01), 18-20, 1996 | 19 | 1996 |
| Compounds and their use as BACE inhibitors SVB Gabor Csjernyik, Sofia Karlstrom, Annika Kers, Karin Kolmodin, Martin ... US Patent 9,248,129, 2016 | 18* | 2016 |
| Compounds and their use as BACE inhibitors G Csjernyik, S Karlstrom, A Kers, K Kolmodin, M Nylof, L Ohberg, L Rakos, ... US Patent 8,865,911, 2014 | 18 | 2014 |
| Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2 S von Berg, Y Xue, M Collins, A Llinas, RI Olsson, T Halvarsson, ... ACS medicinal chemistry letters 10 (6), 972-977, 2019 | 17 | 2019 |
| Synthesis of (−)‐(E, S)‐3‐(Benzyloxy)‐1‐Butenyl Phenyl Sulfone Via a Horner‐Wadsworth‐Emmons Reaction of (−)‐(S)‐2‐(Benzyloxy) Propanal: Benzene,[[[1‐methyl‐3‐(phenylsulfonyl … D Enders, S von Berg, B Jandeleit Organic syntheses 78, 177-177, 2003 | 15 | 2003 |
