Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein JRPM Strating, L van der Linden, L Albulescu, J Bigay, M Arita, L Delang, ... Cell reports 10 (4), 600-615, 2015 | 240 | 2015 |
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells SA Head, W Shi, L Zhao, K Gorshkov, K Pasunooti, Y Chen, Z Deng, R Li, ... Proceedings of the National Academy of Sciences 112 (52), E7276-E7285, 2015 | 118 | 2015 |
Mechanistic insights into the activation of oncogenic forms of EGF receptor Z Wang, PA Longo, MK Tarrant, K Kim, S Head, DJ Leahy, PA Cole Nature structural & molecular biology 18 (12), 1388-1393, 2011 | 101 | 2011 |
Itraconazole side chain analogues: structure–activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 … W Shi, BA Nacev, BT Aftab, S Head, CM Rudin, JO Liu Journal of medicinal chemistry 54 (20), 7363-7374, 2011 | 76 | 2011 |
Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis SA Head, WQ Shi, EJ Yang, BA Nacev, SY Hong, KK Pasunooti, R Li, ... ACS Chemical Biology, 2016 | 74 | 2016 |
Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation QL He, I Minn, Q Wang, P Xu, SA Head, E Datan, B Yu, MG Pomper, ... Angewandte Chemie 128 (39), 12214-12218, 2016 | 71 | 2016 |
Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism JS Shim, RJ Li, J Lv, SA Head, EJ Yang, JO Liu Cancer letters 362 (1), 106-115, 2015 | 28 | 2015 |
Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole JS Shim, RJ Li, NN Bumpus, SA Head, KK Pasunooti, EJ Yang, J Lv, ... Clinical Cancer Research 22 (11), 2709-2720, 2016 | 15 | 2016 |
Insights into the structure–activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moiety H Qiu, S Qian, SA Head, JO Liu, Z Jin Bioorganic & Medicinal Chemistry Letters 26 (19), 4702-4704, 2016 | 9 | 2016 |
Insights into the structure–activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the … S Qian, AK Shah, SA Head, JO Liu, Z Jin Bioorganic & Medicinal Chemistry Letters 26 (15), 3411-3413, 2016 | 9 | 2016 |
Insights into the structure–activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring AK Shah, S Qian, D Zhang, SA Head, JO Liu, Z Jin Bioorganic & medicinal chemistry letters 26 (12), 2890-2892, 2016 | 8 | 2016 |
Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling SA Head, JO Liu JoVE (Journal of Visualized Experiments), e54529-e54529, 2016 | 7 | 2016 |
Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling. BT Aftab, W Shi, BA Nacev, S Head, JO Liu, CM Rudin Molecular Cancer Therapeutics 10 (11 Supplement), C147-C147, 2011 | | 2011 |