Lena Friberg
Lena Friberg
Professor of Pharmacokinetics and Pharmacodynamics, Uppsala University
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Model of chemotherapy-induced myelosuppression with parameter consistency across drugs
LE Friberg, A Henningsson, H Maas, L Nguyen, MO Karlsson
Journal of clinical oncology 20 (24), 4713-4721, 2002
Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by gramá…
D Plachouras, M Karvanen, LE Friberg, E Papadomichelakis, ...
Antimicrobial agents and chemotherapy 53 (8), 3430-3436, 2009
Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial
M Paul, GL Daikos, E Durante-Mangoni, D Yahav, Y Carmeli, YD Benattar, ...
The Lancet Infectious Diseases 18 (4), 391-400, 2018
Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs
EI Nielsen, LE Friberg
Pharmacological reviews 65 (3), 1053-1090, 2013
Application of a loading dose of colistin methanesulfonate in critically ill patients: population pharmacokinetics, protein binding, and prediction of bacterial kill
AF Mohamed, I Karaiskos, D Plachouras, M Karvanen, K Pontikis, ...
Antimicrobial agents and chemotherapy 56 (8), 4241-4249, 2012
Systematic Review and Meta-Analysis of In Vitro Synergy of Polymyxins and Carbapenems
O Zusman, T Avni, L Leibovici, A Adler, L Friberg, T Stergiopoulou, ...
Antimicrobial agents and chemotherapy 57 (10), 5104-5111, 2013
Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization
EI Nielsen, O Cars, LE Friberg
Antimicrobial agents and chemotherapy 55 (10), 4619-4630, 2011
Irinotecan‐induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein
FA De Jong, TJ Scott‐Horton, DL Kroetz, HL McLeod, LE Friberg, ...
Clinical Pharmacology & Therapeutics 81 (1), 42-49, 2007
A review of mixed‐effects models of tumor growth and effects of anticancer drug treatment used in population analysis
B Ribba, NH Holford, P Magni, I Trocˇniz, I Gueorguieva, P Girard, C Sarr, ...
CPT: pharmacometrics & systems pharmacology 3 (5), 1-10, 2014
Integrated population pharmacokinetic analysis of voriconazole in children, adolescents, and adults
LE Friberg, P Ravva, MO Karlsson, P Liu
Antimicrobial agents and chemotherapy 56 (6), 3032-3042, 2012
Cigarette smoking and irinotecan treatment: pharmacokinetic interaction and effects on neutropenia
JM van der Bol, RHJ Mathijssen, WJ Loos, LE Friberg, RHN van Schaik, ...
Journal of Clinical Oncology 25 (19), 2719-2726, 2007
Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes
RHJ Mathijssen, FA De Jong, RHN Van Schaik, ER Lepper, LE Friberg, ...
Journal of the National Cancer Institute 96 (21), 1585-1592, 2004
A Long-term Prospective Population Pharmacokinetic Study on Imatinib Plasma Concentrations in GIST PatientsLong-term Prospective Population PK Study in GIST Patients
K Eechoute, MN Fransson, AK Reyners, FA De Jong, A Sparreboom, ...
Clinical Cancer Research 18 (20), 5780-5787, 2012
Mechanistic models for myelosuppression
LE Friberg, MO Karlsson
Investigational new drugs 21 (2), 183-194, 2003
Impact of CYP2C8* 3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer
TK Bergmann, C Brasch-Andersen, H Green, M Mirza, RS Pedersen, ...
The pharmacogenomics journal 11 (2), 113-120, 2011
Dose response of whole-grain biomarkers: alkylresorcinols in human plasma and their metabolites in urine in relation to intake
R Landberg, P ┼man, LE Friberg, B Vessby, H Adlercreutz, A Kamal-Eldin
The American journal of clinical nutrition 89 (1), 290-296, 2009
Quantitative analysis of colistin A and colistin B in plasma and culture medium using a simple precipitation step followed by LC/MS/MS
B Jansson, M Karvanen, O Cars, D Plachouras, LE Friberg
Journal of pharmaceutical and biomedical analysis 49 (3), 760-767, 2009
Colistin population pharmacokinetics after application of a loading dose of 9 MU colistin methanesulfonate in critically ill patients
I Karaiskos, LE Friberg, K Pontikis, K Ioannidis, V Tsagkari, L Galani, ...
Antimicrobial agents and chemotherapy 59 (12), 7240-7248, 2015
CYP3A4* 22 Genotype and Systemic Exposure Affect Paclitaxel-Induced NeurotoxicityCYP3A4* 22 and Neurotoxicity
AJM de Graan, L Elens, JA Sprowl, A Sparreboom, LE Friberg, ...
Clinical Cancer Research 19 (12), 3316-3324, 2013
Semiphysiological model for the time course of leukocytes after varying schedules of 5-fluorouracil in rats
LE Friberg, A Freijs, M Sandstr÷m, MO Karlsson
Journal of Pharmacology and Experimental Therapeutics 295 (2), 734-740, 2000
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