| De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis BJ Haas, A Papanicolaou, M Yassour, M Grabherr, PD Blood, J Bowden, ... Nature Protocols 8 (8), 1494-1512, 2013 | 6736 | 2013 |
| Mapping intact protein isoforms in discovery mode using top-down proteomics JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ... Nature 480 (7376), 254-258, 2011 | 715 | 2011 |
| ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry L Zamdborg, RD LeDuc, KJ Glowacz, YB Kim, V Viswanathan, ... Nucleic acids research 35 (suppl 2), W701-W706, 2007 | 260 | 2007 |
| ProSight Lite: Graphical software to analyze top‐down mass spectrometry data RT Fellers, JB Greer, BP Early, X Yu, RD LeDuc, NL Kelleher, PM Thomas Proteomics 15 (7), 1235-1238, 2015 | 226 | 2015 |
| ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry RD LeDuc, GK Taylor, YB Kim, TE Januszyk, LH Bynum, JV Sola, ... Nucleic acids research 32 (suppl 2), W340-W345, 2004 | 224 | 2004 |
| Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry JJ Pesavento, CR Bullock, RD LeDuc, CA Mizzen, NL Kelleher Journal of Biological Chemistry 283 (22), 14927-14937, 2008 | 186 | 2008 |
| Identification and Quantification of Proteoforms by Mass Spectrometry LV Schaffer, RJ Millikin, RM Miller, LC Anderson, RT Fellers, Y Ge, ... Proteomics 19 (10), 1800361, 2019 | 149 | 2019 |
| Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. NC Wildburger, TJ Esparza, RD LeDuc, RT Fellers, PM Thomas, ... Scientific reports 7 (1), 9520, 2017 | 125 | 2017 |
| The first pilot project of the consortium for top‐down proteomics: A status report X Dang, J Scotcher, S Wu, RK Chu, N Tolić, I Ntai, PM Thomas, RT Fellers, ... Proteomics 14 (10), 1130-1140, 2014 | 103 | 2014 |
| Applying label-free quantitation to top down proteomics I Ntai, K Kim, RT Fellers, OS Skinner, AD Smith IV, BP Early, JP Savaryn, ... Analytical chemistry 86 (10), 4961-4968, 2014 | 99 | 2014 |
| Identification and characterization of human proteoforms by top-down LC-21 tesla FT-ICR mass spectrometry LC Anderson, CJ DeHart, NK Kaiser, RT Fellers, DF Smith, JB Greer, ... Journal of proteome research 16 (2), 1087-1096, 2017 | 92 | 2017 |
| High-throughput analysis of intact human proteins using UVPD and HCD on an Orbitrap mass spectrometer TP Cleland, CJ DeHart, RT Fellers, AJ VanNispen, JB Greer, RD LeDuc, ... Journal of Proteome Research 16 (5), 2072-2079, 2017 | 89 | 2017 |
| New and automated MS n approaches for top-down identification of modified proteins V Zabrouskov, MW Senko, Y Du, RD Leduc, NL Kelleher Journal of the American Society for Mass Spectrometry 16 (12), 2027-2038, 2005 | 87 | 2005 |
| Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk I Ntai, L Fornelli, CJ DeHart, JE Hutton, PF Doubleday, RD LeDuc, ... Proceedings of the National Academy of Sciences 115 (16), 4140-4145, 2018 | 83 | 2018 |
| Integrated bottom-up and top-down proteomics of patient-derived breast tumor xenografts I Ntai, RD LeDuc, RT Fellers, P Erdmann-Gilmore, SR Davies, J Rumsey, ... Molecular & Cellular Proteomics 15 (1), 45-56, 2016 | 83 | 2016 |
| Advancing top-down analysis of the human proteome using a benchtop quadrupole-Orbitrap mass spectrometer L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ... Journal of Proteome Research 16 (2), 609-618, 2016 | 80 | 2016 |
| The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics RD LeDuc, RT Fellers, BP Early, JB Greer, PM Thomas, NL Kelleher Journal of proteome research 13 (7), 3231-3240, 2014 | 79 | 2014 |
| Trinity RNA-Seq assembler performance optimization R Henschel, M Lieber, LS Wu, PM Nista, BJ Haas, RD LeDuc Proceedings of the 1st Conference of the Extreme Science and Engineering …, 2012 | 75 | 2012 |
| An informatic framework for decoding protein complexes by top-down mass spectrometry OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ... Nature methods 13 (3), 237-240, 2016 | 72 | 2016 |
| A comprehensive pipeline for translational top-down proteomics from a single blood draw TK Toby, L Fornelli, S Kristina, CJ DeHart, RT Fellers, RD LeDuc, ... Nature Protocols, 2016 | 63 | 2016 |
Neil KelleherProfessor of Chemistry, Northwestern UniversityVerified email at integratedproteintechnologies.com
