Molecular characterization of the Arabidopsis 9‐cis epoxycarotenoid dioxygenase gene family BC Tan, LM Joseph, WT Deng, L Liu, QB Li, K Cline, DR McCarty The Plant Journal 35 (1), 44-56, 2003 | 943 | 2003 |
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa WA Beltran, AV Cideciyan, AS Lewin, S Iwabe, H Khanna, A Sumaroka, ... Proceedings of the National Academy of Sciences 109 (6), 2132-2137, 2012 | 324 | 2012 |
Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina H Petrs-Silva, A Dinculescu, Q Li, WT Deng, J Pang, SH Min, V Chiodo, ... Molecular Therapy 19 (2), 293-301, 2011 | 309 | 2011 |
Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial NG Ghazi, EB Abboud, SR Nowilaty, H Alkuraya, A Alhommadi, H Cai, ... Human genetics 135, 327-343, 2016 | 271 | 2016 |
AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEβ mutation J Pang, SL Boye, A Kumar, A Dinculescu, W Deng, J Li, Q Li, A Rani, ... Investigative ophthalmology & visual science 49 (10), 4278-4283, 2008 | 165 | 2008 |
AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia J Pang, WT Deng, X Dai, B Lei, D Everhart, Y Umino, J Li, K Zhang, S Mao, ... PloS one 7 (4), e35250, 2012 | 137 | 2012 |
Comparative analysis of in vivo and in vitro AAV vector transduction in the neonatal mouse retina: effects of serotype and site of administration J Pang, A Lauramore, W Deng, Q Li, TJ Doyle, V Chiodo, J Li, ... Vision research 48 (3), 377-385, 2008 | 114 | 2008 |
Preclinical Potency and Safety Studies of an AAV2-Mediated Gene Therapy Vector for the Treatment of MERTK Associated Retinitis Pigmentosa TJ Conlon, WT Deng, K Erger, T Cossette, J Pang, R Ryals, N Clément, ... Human gene therapy Clinical development 24 (1), 23-28, 2013 | 108 | 2013 |
Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California) G Lutty, T Chan-Ling, D Phelps, A Adamis, K Berns, C Chan, C Cole, ... Molecular vision 12 (63), 532-580, 2006 | 93 | 2006 |
Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease WA Beltran, AV Cideciyan, S Iwabe, M Swider, MS Kosyk, K McDaid, ... Proceedings of the National Academy of Sciences 112 (43), E5844-E5853, 2015 | 84 | 2015 |
Stability and Safety of an AAV Vector for Treating RPGR-ORF15 X-Linked Retinitis Pigmentosa WT Deng, FM Dyka, A Dinculescu, J Li, P Zhu, VA Chiodo, SL Boye, ... Human gene therapy 26 (9), 593-602, 2015 | 68 | 2015 |
Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats WT Deng, A Dinculescu, Q Li, SL Boye, J Li, MS Gorbatyuk, J Pang, ... Investigative ophthalmology & visual science 53 (4), 1895-1904, 2012 | 65 | 2012 |
Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light ES Lobanova, R Herrmann, S Finkelstein, B Reidel, NP Skiba, WT Deng, ... Journal of Neuroscience 30 (20), 6815-6824, 2010 | 64 | 2010 |
Achromatopsia as a potential candidate for gene therapy JJ Pang, J Alexander, B Lei, W Deng, K Zhang, Q Li, B Chang, ... Retinal Degenerative Diseases: Laboratory and Therapeutic Investigations …, 2010 | 63 | 2010 |
Functional interchangeability of rod and cone transducin α-subunits WT Deng, K Sakurai, J Liu, A Dinculescu, J Li, J Pang, SH Min, VA Chiodo, ... Proceedings of the National Academy of Sciences 106 (42), 17681-17686, 2009 | 54 | 2009 |
Gene Therapy for Retinitis Pigmentosa Caused by MFRP Mutations: Human Phenotype and Preliminary Proof of Concept A Dinculescu, J Estreicher, JC Zenteno, TS Aleman, SB Schwartz, ... Human gene therapy 23 (4), 367-376, 2012 | 50 | 2012 |
Gene Therapy for MERTK-Associated Retinal Degenerations MM LaVail, D Yasumura, MT Matthes, H Yang, WW Hauswirth, WT Deng, ... Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 487-493, 2016 | 42 | 2016 |
Gene-based therapy in a mouse model of blue cone monochromacy Y Zhang, WT Deng, W Du, P Zhu, J Li, F Xu, J Sun, CD Gerstner, W Baehr, ... Scientific reports 7 (1), 6690, 2017 | 41 | 2017 |
AAV-mediated lysophosphatidylcholine acyltransferase 1 (Lpcat1) gene replacement therapy rescues retinal degeneration in rd11 mice X Dai, J Han, Y Qi, H Zhang, L Xiang, J Lv, J Li, WT Deng, B Chang, ... Investigative ophthalmology & visual science 55 (3), 1724-1734, 2014 | 31 | 2014 |
Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3−/−/Nrl−/− mice, an all-cone model of CNGA3 achromatopsia W Du, Y Tao, WT Deng, P Zhu, J Li, X Dai, Y Zhang, W Shi, X Liu, ... Human molecular genetics 24 (13), 3699-3707, 2015 | 29 | 2015 |