Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients J Stebbing, V Krishnan, S de Bono, S Ottaviani, G Casalini, ... EMBO molecular medicine 12 (8), e12697, 2020 | 284 | 2020 |
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality J Stebbing, G Sánchez Nievas, M Falcone, S Youhanna, P Richardson, ... Science advances 7 (1), eabe4724, 2021 | 197 | 2021 |
Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19 JT Sims, V Krishnan, CY Chang, SM Engle, G Casalini, GH Rodgers, ... Journal of Allergy and Clinical Immunology 147 (1), 107-111, 2021 | 161 | 2021 |
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts L Pellegrino, J Stebbing, VM Braga, AE Frampton, J Jacob, L Buluwela, ... Nucleic acids research 41 (10), 5400-5412, 2013 | 134 | 2013 |
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression S Ottaviani, J Stebbing, AE Frampton, S Zagorac, J Krell, A de Giorgio, ... Nature communications 9 (1), 1845, 2018 | 112 | 2018 |
ICEC0942, an orally bioavailable selective inhibitor of CDK7 for cancer treatment H Patel, M Periyasamy, GP Sava, A Bondke, BW Slafer, SHB Kroll, ... Molecular cancer therapeutics 17 (6), 1156-1166, 2018 | 108 | 2018 |
Growth Arrest-Specific Transcript 5 Associated snoRNA Levels Are Related to p53 Expression and DNA Damage in Colorectal Cancer J Krell, AE Frampton, R Mirnezami, V Harding, A De Giorgio, ... PloS one 9 (6), e98561, 2014 | 89 | 2014 |
MicroRNAs associated with small bowel neuroendocrine tumours and their metastases HC Miller, AE Frampton, A Malczewska, S Ottaviani, EA Stronach, R Flora, ... Endocr Relat Cancer 23 (9), 711-726, 2016 | 65 | 2016 |
Therapeutic potential of targeting SK1 in human cancers H Alshaker, L Sauer, D Monteil, S Ottaviani, S Srivats, T Böhler, ... Advances in cancer research 117, 143-200, 2013 | 60 | 2013 |
A real-world disproportionality analysis of FDA Adverse Event Reporting System (FAERS) events for baricitinib L Peng, K Xiao, S Ottaviani, J Stebbing, YJ Wang Expert Opinion on Drug Safety 19 (11), 1505-1511, 2020 | 47 | 2020 |
Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells CF Lai, KD Flach, X Alexi, SP Fox, S Ottaviani, PTR Thiruchelvam, FJ Kyle, ... Nucleic acids research 41 (22), 10228-10240, 2013 | 46 | 2013 |
CNS penetration of potential anti-COVID-19 drugs PJ Richardson, S Ottaviani, A Prelle, J Stebbing, G Casalini, M Corbellino Journal of Neurology 267 (7), 1880-1882, 2020 | 43 | 2020 |
Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer ML Lin, H Patel, J Remenyi, CRS Banerji, CF Lai, M Periyasamy, ... Oncotarget 6 (25), 21685, 2015 | 30 | 2015 |
SCIRT lncRNA restrains tumorigenesis by opposing transcriptional programs of tumor-initiating cells S Zagorac, A de Giorgio, A Dabrowska, M Kalisz, N Casas-Vila, ... Cancer Research 81 (3), 580-593, 2021 | 21 | 2021 |
Noncoding RNAs and the control of signalling via nuclear receptor regulation in health and disease P Cathcart, W Lucchesi, S Ottaviani, A De Giorgio, J Krell, J Stebbing, ... Best practice & research Clinical endocrinology & metabolism 29 (4), 529-543, 2015 | 21 | 2015 |
Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells S Ottaviani, GN Brooke, C O'Hanlon-Brown, J Waxman, S Ali, L Buluwela Journal of molecular endocrinology 51 (3), 301-312, 2013 | 21 | 2013 |
Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer S Chrysostomou, R Roy, F Prischi, L Thamlikitkul, KL Chapman, U Mufti, ... Science translational medicine 13 (602), eaba4627, 2021 | 18 | 2021 |
Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR L Castellano, A Dabrowska, L Pellegrino, S Ottaviani, P Cathcart, ... Nucleic acids research 45 (8), 4401-4412, 2017 | 16 | 2017 |
Noncoding RNAs and the control of hormonal signaling via nuclear receptor regulation S Ottaviani, A de Giorgio, V Harding, J Stebbing, L Castellano J Mol Endocrinol 53 (2), R61-70, 2014 | 15 | 2014 |
microRNAs: Novel regulators of the TGF-β pathway in pancreatic ductal adenocarcinoma S Ottaviani, L Castellano Molecular & Cellular Oncology 5 (6), e1499066, 2018 | 9 | 2018 |