Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy JK Lee, Z Liu, JK Sa, S Shin, J Wang, M Bordyuh, HJ Cho, O Elliott, T Chu, ... Nature genetics 50 (10), 1399-1411, 2018 | 172 | 2018 |
Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells MJ Yoon, AR Lee, SA Jeong, YS Kim, JY Kim, YJ Kwon, KS Choi Oncotarget 5 (16), 6816, 2014 | 129 | 2014 |
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology A Golebiewska, AC Hau, A Oudin, D Stieber, YA Yabo, V Baus, ... Acta Neuropathologica 140, 919-949, 2020 | 88 | 2020 |
Patient-derived xenografts from non–small cell lung cancer brain metastases are valuable translational platforms for the development of personalized targeted therapy HW Lee, J Lee, SJ Lee, HJ Cho, HJ Song, DE Jeong, YJ Seo, S Shin, ... Clinical cancer research 21 (5), 1172-1182, 2015 | 77 | 2015 |
Automated genome-wide visual profiling of cellular proteins involved in HIV infection A Genovesio, YJ Kwon, MP Windisch, NY Kim, SY Choi, HC Kim, S Jung, ... Journal of biomolecular screening 16 (9), 945-958, 2011 | 65 | 2011 |
Intracellular protein target detection by quantum dots optimized for live cell imaging Y Choi, K Kim, S Hong, H Kim, YJ Kwon, R Song Bioconjugate Chemistry 22 (8), 1576-1586, 2011 | 64 | 2011 |
Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window AK Singh, RK Pandey, JL Siqueira-Neto, YJ Kwon, LH Freitas-Junior, ... Infection and immunity 83 (5), 1853-1868, 2015 | 55 | 2015 |
Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection A Genovesio, MA Giardini, YJ Kwon, FM Dossin, SY Choi, NY Kim, ... PloS one 6 (5), e19733, 2011 | 39 | 2011 |
CXCL10 is an agonist of the CC family chemokine scavenger receptor ACKR2/D6 A Chevigné, B Janji, M Meyrath, N Reynders, G D’uonnolo, T Uchański, ... Cancers 13 (5), 1054, 2021 | 31 | 2021 |
Kinome siRNA screen identifies novel cell-type specific dengue host target genes YJ Kwon, J Heo, HEE Wong, DJM Cruz, S Velumani, CT da Silva, ... Antiviral Research 110, 20-30, 2014 | 24 | 2014 |
Phosphorylation of CREB, a cyclic AMP responsive element binding protein, contributes partially to lysophosphatidic acid-induced fibroblast cell proliferation YJ Kwon, Y Sun, NH Kim, SO Huh Biochemical and biophysical research communications 380 (3), 655-659, 2009 | 17 | 2009 |
Patient-derived tumor organoids for guidance of personalized drug therapies in recurrent glioblastoma M Ratliff, H Kim, H Qi, M Kim, B Ku, DD Azorin, D Hausmann, RK Khajuria, ... International journal of molecular sciences 23 (12), 6572, 2022 | 15 | 2022 |
Quantum Dot‐Based Screening System for Discovery of G Protein‐Coupled Receptor Agonists J Lee, YJ Kwon, Y Choi, HC Kim, K Kim, JY Kim, S Park, R Song ChemBioChem 13 (10), 1503-1508, 2012 | 12 | 2012 |
High-content classification of nucleocytoplasmic import or export inhibitors YJ Kwon, A Genovesio, N Youl Kim, HC Kim, S Jung, B David-Watine, ... Journal of biomolecular screening 12 (5), 621-627, 2007 | 11 | 2007 |
Revealing invisible cell phenotypes with conditional generative modeling A Lamiable, T Champetier, F Leonardi, E Cohen, P Sommer, D Hardy, ... Nature Communications 14 (1), 6386, 2023 | 10 | 2023 |
High-content phenotyping of Parkinson's disease patient stem cell-derived midbrain dopaminergic neurons using machine learning classification A Vuidel, L Cousin, B Weykopf, S Haupt, Z Hanifehlou, N Wiest-Daesslé, ... Stem Cell Reports 17 (10), 2349-2364, 2022 | 10 | 2022 |
Drug efficacy comparison of 3D forming and preforming sphere models with a micropillar and microwell chip platform I Doh, YJ Kwon, B Ku, DW Lee SLAS DISCOVERY: Advancing Life Sciences R&D 24 (4), 476-483, 2019 | 10 | 2019 |
RNAi screening-based identification of USP10 as a novel regulator of paraptosis JY Kim, DM Lee, HG Woo, KD Kim, HJ Lee, YJ Kwon, KS Choi Scientific Reports 9 (1), 4909, 2019 | 9 | 2019 |
Robust dose-response curve estimation applied to high content screening data analysis TT Nguyen, K Song, Y Tsoy, JY Kim, YJ Kwon, M Kang, ... Source code for biology and medicine 9, 1-9, 2014 | 9 | 2014 |
Development of a cell-defined siRNA microarray for analysis of gene function in human bone marrow stromal cells HC Kim, GH Kim, SG Cho, EJ Lee, YJ Kwon Stem Cell Research 16 (2), 365-376, 2016 | 7 | 2016 |