Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat R Teperino, S Amann, M Bayer, SL McGee, A Loipetzberger, T Connor, ... Cell 151 (2), 414-426, 2012 | 282 | 2012 |
Histone methyl transferases and demethylases; can they link metabolism and transcription? R Teperino, K Schoonjans, J Auwerx Cell metabolism 12 (4), 321-327, 2010 | 281 | 2010 |
Trim28 haploinsufficiency triggers bi-stable epigenetic obesity K Dalgaard, K Landgraf, S Heyne, A Lempradl, J Longinotto, K Gossens, ... Cell 164 (3), 353-364, 2016 | 210 | 2016 |
Canonical and non-canonical Hedgehog signalling and the control of metabolism R Teperino, F Aberger, H Esterbauer, N Riobo, JA Pospisilik Seminars in cell & developmental biology 33, 81-92, 2014 | 154 | 2014 |
The polycomb-dependent epigenome controls β cell dysfunction, dedifferentiation, and diabetes TTH Lu, S Heyne, E Dror, E Casas, L Leonhardt, T Boenke, CH Yang, ... Cell Metabolism 27 (6), 1294-1308. e7, 2018 | 128 | 2018 |
Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells GA Raciti, C Iadicicco, L Ulianich, BF Vind, M Gaster, F Andreozzi, ... Diabetologia 53, 955-965, 2010 | 69 | 2010 |
MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption M Posavec Marjanović, S Hurtado-Bagès, M Lassi, V Valero, R Malinverni, ... Nature structural & molecular biology 24 (11), 902-910, 2017 | 61 | 2017 |
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol kinase subcellular localization C Miele, F Paturzo, R Teperino, F Sakane, F Fiory, P Ungaro, R Valentino, ... Journal of biological chemistry 282 (44), 31835-31843, 2007 | 61 | 2007 |
Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis J Todoric, B Strobl, A Jais, N Boucheron, M Bayer, S Amann, J Lindroos, ... Diabetes 60 (6), 1668-1676, 2011 | 54 | 2011 |
Bridging epigenomics and complex disease: the basics R Teperino, A Lempradl, JA Pospisilik Cellular and Molecular Life Sciences 70, 1609-1621, 2013 | 48 | 2013 |
Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells F Viparelli, A Cassese, N Doti, F Paturzo, D Marasco, NA Dathan, ... Journal of biological chemistry 283 (31), 21769-21778, 2008 | 45 | 2008 |
The aging mouse microbiome has obesogenic characteristics D Binyamin, N Werbner, M Nuriel-Ohayon, A Uzan, H Mor, A Abbas, O Ziv, ... Genome medicine 12, 1-9, 2020 | 34 | 2020 |
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue A Georgiadi, V Lopez-Salazar, RE Merahbi, RA Karikari, X Ma, A Mourão, ... Nature communications 12 (1), 2999, 2021 | 30 | 2021 |
Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4α and chicken ovalbumin upstream … P Ungaro, R Teperino, P Mirra, A Cassese, F Fiory, G Perruolo, C Miele, ... Journal of biological chemistry 283 (45), 30970-30979, 2008 | 29 | 2008 |
Oriente F, Ungaro P, Valentino R, Beguinot F, Formisano P. Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol … C Miele, F Paturzo, R Teperino, F Sakane, F Fiory J Biol Chem 282, 31835-31843, 2007 | 28 | 2007 |
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation A Perfetti, S Iovino, AT Alberobello, APM Barbagallo, I Esposito, F Fiory, ... Journal of biological chemistry 282 (12), 8648-8657, 2007 | 24 | 2007 |
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density AL Swan, C Schütt, J Rozman, M del Mar Muñiz Moreno, S Brandmaier, ... PLoS genetics 16 (12), e1009190, 2020 | 22 | 2020 |
Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis E Marbach-Breitrück, M Matz-Soja, U Abraham, W Schmidt-Heck, S Sales, ... Journal of hepatology 70 (6), 1192-1202, 2019 | 22 | 2019 |
Hepatocyte nuclear factor (HNF)-4α-driven epigenetic silencing of the human PED gene P Ungaro, R Teperino, P Mirra, M Longo, M Ciccarelli, GA Raciti, C Nigro, ... Diabetologia 53, 1482-1492, 2010 | 22 | 2010 |
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy N Spielmann, G Miller, TI Oprea, CW Hsu, G Fobo, G Frishman, ... Nature Cardiovascular Research 1 (2), 157-173, 2022 | 21 | 2022 |