John Fowlkes
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Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues
KM Thrailkill, CK Lumpkin Jr, RC Bunn, SF Kemp, JL Fowlkes
American journal of physiology-endocrinology and metabolism 289 (5), E735-E745, 2005
Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.
JL Fowlkes, JJ Enghild, K Suzuki, H Nagase
Journal of Biological Chemistry 269 (41), 25742-25746, 1994
Insulin-like growth factor binding protein proteolysis
RC Bunn, JL Fowlkes
Trends in Endocrinology & Metabolism 14 (4), 176-181, 2003
Matrix metalloproteinases: their potential role in the pathogenesis of diabetic nephropathy
KM Thrailkill, R Clay Bunn, JL Fowlkes
Endocrine 35, 1-10, 2009
Bone formation is impaired in a model of type 1 diabetes
KM Thrailkill, L Liu, EC Wahl, RC Bunn, DS Perrien, GE Cockrell, ...
Diabetes 54 (10), 2875-2881, 2005
Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation
KM Thrailkill, LD Quarles, H Nagase, K Suzuki, DM Serra, JL Fowlkes
Endocrinology 136 (8), 3527-3533, 1995
Enhanced excretion of vitamin D binding protein in type 1 diabetes: a role in vitamin D deficiency?
KM Thrailkill, CH Jo, GE Cockrell, CS Moreau, JL Fowlkes
The Journal of Clinical Endocrinology & Metabolism 96 (1), 142-149, 2011
Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases
JL Fowlkes, KM Thrailkill, DM Serra, K Suzuki, H Nagase
Progress in growth factor research 6 (2-4), 255-263, 1995
Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1
DC Martin, JL Fowlkes, B Babic, R Khokha
The Journal of cell biology 146 (4), 881-892, 1999
Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: kinetics of IGFBP-3 binding and identification of receptor …
Y Yamanaka, JL Fowlkes, EM Wilson, RG Rosenfeld, Y Oh
Endocrinology 140 (3), 1319-1328, 1999
Proteolysis of insulin-like growth factor binding protein-3 during rat pregnancy: a role for matrix metalloproteinases
JL Fowlkes, K Suzuki, H Nagase, KM Thrailkill
Endocrinology 135 (6), 2810-2813, 1994
Matrix metalloproteinase-2 dysregulation in type 1 diabetes
KM Thrailkill, RC Bunn, CS Moreau, GE Cockrell, PM Simpson, ...
Diabetes care 30 (9), 2321-2326, 2007
A type 1 diabetes genetic risk score predicts progression of islet autoimmunity and development of type 1 diabetes in individuals at risk
MJ Redondo, S Geyer, AK Steck, S Sharp, JM Wentworth, MN Weedon, ...
Diabetes care 41 (9), 1887-1894, 2018
Increasing duration of type 1 diabetes perturbs the strength–structure relationship and increases brittleness of bone
JS Nyman, JL Even, CH Jo, EG Herbert, MR Murry, GE Cockrell, EC Wahl, ...
Bone 48 (4), 733-740, 2011
Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are down-regulated throughout osteogenesis in type 1 diabetes mellitus
JL Fowlkes, RC Bunn, L Liu, EC Wahl, HN Coleman, GE Cockrell, ...
Endocrinology 149 (4), 1697-1704, 2008
Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts
J Fowlkes, M Freemark
Endocrinology 131 (5), 2071-2076, 1992
Microalbuminuria in type 1 diabetes is associated with enhanced excretion of the endocytic multiligand receptors megalin and cubilin
KM Thrailkill, T Nimmo, RC Bunn, GE Cockrell, CS Moreau, S Mackintosh, ...
Diabetes care 32 (7), 1266-1268, 2009
Disease and gender-specific dysregulation of NGAL and MMP-9 in type 1 diabetes mellitus
KM Thrailkill, CS Moreau, GE Cockrell, CH Jo, RC Bunn, ...
Endocrine 37, 336-343, 2010
Heparin-binding, highly basic regions within the thyroglobulin type-1 repeat of insulin-like growth factor (IGF)-binding proteins (IGFBPs)-3,-5, and-6 inhibit IGFBP-4 degradation
JL Fowlkes, KM Thrailkill, C George-Nascimento, CK Rosenberg, ...
Endocrinology 138 (6), 2280-2285, 1997
Palmitate and insulin synergistically induce IL-6 expression in human monocytes
RC Bunn, GE Cockrell, Y Ou, KM Thrailkill, CK Lumpkin, JL Fowlkes
Cardiovascular Diabetology 9, 1-13, 2010
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