Michiel Niesen
Michiel Niesen
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Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment
I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan
Structure 19 (8), 1108-1126, 2011
Comparison of two highly-effective mRNA vaccines for COVID-19 during periods of Alpha and Delta variant prevalence
A Puranik, PJ Lenehan, E Silvert, MJM Niesen, J Corchado-Garcia, ...
MedRxiv, 2021
FDA-authorized mRNA COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system
C Pawlowski, P Lenehan, A Puranik, V Agarwal, AJ Venkatakrishnan, ...
Med 2 (8), 979-992. e8, 2021
The role of conformational ensembles in ligand recognition in G-protein coupled receptors
MJM Niesen, S Bhattacharya, N Vaidehi
Journal of the American Chemical Society 133 (33), 13197-13204, 2011
Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin
AJ Venkatakrishnan, P Anand, P Lenehan, R Suratekar, B Raghunathan, ...
OSF, 2021
Forces on nascent polypeptides during membrane insertion and translocation via the Sec translocon
MJM Niesen, A Müller-Lucks, R Hedman, G von Heijne, TF Miller
Biophysical Journal 115 (10), 1885-1894, 2018
COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance
MJM Niesen, P Anand, E Silvert, R Suratekar, C Pawlowski, P Ghosh, ...
MedRxiv, 2021.07. 01.21259833, 2021
Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integration
MJM Niesen, CY Wang, RC Van Lehn, TF Miller III
PLoS computational biology 13 (3), e1005427, 2017
Water orientation and dynamics in the closed and open influenza B virus M2 proton channels
MD Gelenter, VS Mandala, MJM Niesen, DA Sharon, AJ Dregni, ...
Communications Biology 4 (1), 338, 2021
Critical analysis of the successes and failures of homology models of G protein‐coupled receptors
S Bhattacharya, AR Lam, H Li, G Balaraman, MJM Niesen, N Vaidehi
Proteins: Structure, Function, and Bioinformatics 81 (5), 729-739, 2013
Surveillance of safety of 3 doses of COVID-19 mRNA vaccination using electronic health records
MJM Niesen, C Pawlowski, JC O’Horo, DW Challener, E Silvert, ...
JAMA network open 5 (4), e227038-e227038, 2022
High diversity in Delta variant across countries revealed by genome‐wide analysis of SARS‐CoV‐2 beyond the Spike protein
R Suratekar, P Ghosh, MJM Niesen, G Donadio, P Anand, ...
Molecular systems biology 18 (2), e10673, 2022
Advanced techniques for constrained internal coordinate molecular dynamics
JR Wagner, GS Balaraman, MJM Niesen, AB Larsen, A Jain, N Vaidehi
Journal of computational chemistry 34 (11), 904-914, 2013
Comparative effectiveness of mRNA-1273 and BNT162b2 against symptomatic SARS-CoV-2 infection
A Puranik, PJ Lenehan, E Silvert, MJM Niesen, J Corchado-Garcia, ...
Med 3 (1), 28-41. e8, 2022
Water dynamics around proteins: T-and R-states of hemoglobin and melittin
M Pezzella, K El Hage, MJM Niesen, S Shin, AP Willard, M Meuwly, ...
The Journal of Physical Chemistry B 124 (30), 6540-6554, 2020
A link between integral membrane protein expression and simulated integration efficiency
SS Marshall, MJM Niesen, A Müller, K Tiemann, SM Saladi, RP Galimidi, ...
Cell Reports 16 (8), 2169-2177, 2016
Durability analysis of the highly effective BNT162b2 vaccine against COVID-19
A Puranik, PJ Lenehan, JC O'Horo, C Pawlowski, MJM Niesen, A Virk, ...
PNAS nexus 1 (3), pgac082, 2022
Thermostabilization of the β1-Adrenergic Receptor Correlates with Increased Entropy of the Inactive State
MJM Niesen, S Bhattacharya, R Grisshammer, CG Tate, N Vaidehi
The Journal of Physical Chemistry B 117 (24), 7283-7291, 2013
Improving membrane protein expression by optimizing integration efficiency
MJM Niesen, SS Marshall, TF Miller, WM Clemons
Journal of Biological Chemistry 292 (47), 19537-19545, 2017
On the origins of omicron’s unique spike gene insertion
AJ Venkatakrishnan, P Anand, PJ Lenehan, R Suratekar, B Raghunathan, ...
Vaccines 10 (9), 1509, 2022
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