Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes E Bernard, Y Nannya, RP Hasserjian, SM Devlin, H Tuechler, ... Nature medicine 26 (10), 1549-1556, 2020 | 466 | 2020 |
Cancer therapy shapes the fitness landscape of clonal hematopoiesis KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ... Nature genetics 52 (11), 1219-1226, 2020 | 438 | 2020 |
Molecular international prognostic scoring system for myelodysplastic syndromes E Bernard, H Tuechler, PL Greenberg, RP Hasserjian, JE Arango Ossa, ... NEJM evidence 1 (7), EVIDoa2200008, 2022 | 416 | 2022 |
Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ... Cancer cell 33 (1), 29-43. e7, 2018 | 280 | 2018 |
Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis T Gao, R Ptashkin, KL Bolton, M Sirenko, C Fong, B Spitzer, ... Nature communications 12 (1), 338, 2021 | 80 | 2021 |
Functional impact of diaphragm muscle sarcopenia in both male and female mice SM Greising, CB Mantilla, JS Medina-Martínez, JM Stowe, GC Sieck American Journal of Physiology-Lung Cellular and Molecular Physiology 309 (1 …, 2015 | 78 | 2015 |
Analysis of muscle fiber clustering in the diaphragm muscle of sarcopenic mice SM Greising, JS Medina‐Martínez, AK Vasdev, GC Sieck, CB Mantilla Muscle & nerve 52 (1), 76-82, 2015 | 58 | 2015 |
Impact of high-molecular-risk mutations on transplantation outcomes in patients with myelofibrosis R Tamari, F Rapaport, N Zhang, C McNamara, A Kuykendall, DA Sallman, ... Biology of Blood and Marrow Transplantation 25 (6), 1142-1151, 2019 | 57 | 2019 |
Phase 2 study of ruxolitinib and decitabine in patients with myeloproliferative neoplasm in accelerated and blast phase JO Mascarenhas, RK Rampal, HE Kosiorek, R Bhave, E Hexner, ... Blood advances 4 (20), 5246-5256, 2020 | 51 | 2020 |
Comprehensive detection of recurring genomic abnormalities: a targeted sequencing approach for multiple myeloma V Yellapantula, M Hultcrantz, EH Rustad, E Wasserman, D Londono, ... Blood cancer journal 9 (12), 101, 2019 | 51 | 2019 |
Accelerated single cell seeding in relapsed multiple myeloma HJ Landau, V Yellapantula, BT Diamond, EH Rustad, KH Maclachlan, ... Nature communications 11 (1), 3617, 2020 | 45 | 2020 |
PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation W Xiao, M Bharadwaj, M Levine, N Farnoud, F Pastore, BM Getta, ... Blood Advances 2 (23), 3526-3539, 2018 | 45 | 2018 |
Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers N Shukla, MF Levine, G Gundem, D Domenico, B Spitzer, N Bouvier, ... Nature communications 13 (1), 2485, 2022 | 30 | 2022 |
Isabl Platform, a digital biobank for processing multimodal patient data JS Medina-Martínez, JE Arango-Ossa, MF Levine, Y Zhou, G Gundem, ... BMC bioinformatics 21, 1-18, 2020 | 28 | 2020 |
TP53 state dictates genome stability, clinical presentation and outcomes in myelodysplastic syndromes E Bernard, Y Nannya, T Yoshizato, RP Hasserjian, R Saiki, Y Shiozawa, ... Blood 134, 675, 2019 | 23 | 2019 |
Oncologic therapy shapes the fitness landscape of clonal hematopoiesis KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ... BioRxiv, 848739, 2019 | 22 | 2019 |
Transient expansion of TP53 mutated clones in polycythemia vera patients treated with idasanutlin BK Marcellino, N Farnoud, B Cassinat, M Lu, E Verger, E McGovern, ... Blood advances 4 (22), 5735-5744, 2020 | 21 | 2020 |
Semi-automated assessment of transdiaphragmatic pressure variability across motor behaviors JS Medina-Martínez, SM Greising, GC Sieck, CB Mantilla Respiratory physiology & neurobiology 215, 73-81, 2015 | 17 | 2015 |
Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia F Rapaport, Y Neelamraju, T Baslan, D Hassane, A Gruszczynska, ... Leukemia 35 (9), 2688-2692, 2021 | 12 | 2021 |
Clonal evolution during metastatic spread in high-risk neuroblastoma G Gundem, MF Levine, SS Roberts, IY Cheung, JS Medina-Martínez, ... Nature genetics 55 (6), 1022-1033, 2023 | 9 | 2023 |