Follow
Brian Kobilka
Brian Kobilka
Verified email at stanford.edu
Title
Cited by
Cited by
Year
High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor
V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1258-1265, 2007
40852007
Crystal structure of the β2 adrenergic receptor–Gs protein complex
SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ...
Nature 477 (7366), 549-555, 2011
34462011
The structure and function of G-protein-coupled receptors
DM Rosenbaum, SGF Rasmussen, BK Kobilka
Nature 459 (7245), 356-363, 2009
29632009
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
SGF Rasmussen, HJ Choi, DM Rosenbaum, TS Kobilka, FS Thian, ...
Nature 450 (7168), 383-387, 2007
26062007
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ...
Nature 469 (7329), 175-180, 2011
19952011
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1266-1273, 2007
17542007
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ...
Nature 321 (6065), 75-79, 1986
17501986
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
A Manglik, AC Kruse, TS Kobilka, FS Thian, JM Mathiesen, RK Sunahara, ...
Nature 485 (7398), 321-326, 2012
15912012
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
13142007
βAR signaling required for diet-induced thermogenesis and obesity resistance
ES Bachman, H Dhillon, CY Zhang, S Cinti, AC Bianco, BK Kobilka, ...
Science 297 (5582), 843-845, 2002
10512002
Chimeric α2-,β2-Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity
BK Kobilka, TS Kobilka, K Daniel, JW Regan, MG Caron, RJ Lefkowitz
Science 240 (4857), 1310-1316, 1988
10501988
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α2-Adrenergic Receptor
BK Kobilka, H Matsui, TS Kobilka, TL Yang-Feng, U Francke, MG Caron, ...
Science 238 (4827), 650-656, 1987
9981987
The molecular basis of G protein–coupled receptor activation
WI Weis, BK Kobilka
Annual review of biochemistry 87 (1), 897-919, 2018
9842018
Structure-based discovery of opioid analgesics with reduced side effects
A Manglik, H Lin, DK Aryal, JD McCorvy, D Dengler, G Corder, A Levit, ...
Nature 537 (7619), 185-190, 2016
9742016
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101-106, 2013
9572013
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the …
BK Kobilka, RA Dixon, T Frielle, HG Dohlman, MA Bolanowski, IS Sigal, ...
Proceedings of the National Academy of Sciences 84 (1), 46-50, 1987
9251987
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
K Haga, AC Kruse, H Asada, T Yurugi-Kobayashi, M Shiroishi, C Zhang, ...
Nature 482 (7386), 547-551, 2012
9232012
Structure and dynamics of the M3 muscarinic acetylcholine receptor
AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ...
Nature 482 (7386), 552-556, 2012
9152012
G protein coupled receptor structure and activation
BK Kobilka
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (4), 794-807, 2007
9142007
Structure and dynamics of GPCR signaling complexes
D Hilger, M Masureel, BK Kobilka
Nature structural & molecular biology 25 (1), 4-12, 2018
9112018
The system can't perform the operation now. Try again later.
Articles 1–20