Diarmaid Hughes
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Antibiotic resistance and its cost: is it possible to reverse resistance?
DI Andersson, D Hughes
Nature Reviews Microbiology 8 (4), 260-271, 2010
Selection of resistant bacteria at very low antibiotic concentrations
E Gullberg, S Cao, OG Berg, C Ilbäck, L Sandegren, D Hughes, ...
PLoS pathogens 7 (7), e1002158, 2011
Microbiological effects of sublethal levels of antibiotics
DI Andersson, D Hughes
Nature Reviews Microbiology 12 (7), 465-478, 2014
Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance
J Bjorkman, I Nagaev, OG Berg, D Hughes, DI Andersson
Science 287 (5457), 1479-1482, 2000
Mechanisms and consequences of bacterial resistance to antimicrobial peptides
DI Andersson, D Hughes, JZ Kubicek-Sutherland
Drug Resistance Updates 26, 43-57, 2016
Persistence of antibiotic resistance in bacterial populations
DI Andersson, D Hughes
FEMS microbiology reviews 35 (5), 901-911, 2011
Mutation Rate and Evolution of Fluoroquinolone Resistance in Escherichia coli Isolates from Patients with Urinary Tract Infections
P Komp Lindgren, ASA Karlsson, D Hughes
Antimicrobial agents and chemotherapy 47 (10), 3222-3232, 2003
Virulence of antibiotic-resistant Salmonella typhimurium
J Björkman, D Hughes, DI Andersson
Proceedings of the National Academy of Sciences 95 (7), 3949-3953, 1998
Evolution of antibiotic resistance at non-lethal drug concentrations
DI Andersson, D Hughes
Drug resistance updates 15 (3), 162-172, 2012
Interplay in the selection of fluoroquinolone resistance and bacterial fitness
LL Marcusson, N Frimodt-Møller, D Hughes
PLoS Pathogens 5 (8), e1000541, 2009
Biological cost and compensatory evolution in fusidic acid‐resistant Staphylococcus aureus
I Nagaev, J Björkman, DI Andersson, D Hughes
Molecular microbiology 40 (2), 433-439, 2001
Gene amplification and adaptive evolution in bacteria
DI Andersson, D Hughes
Annual review of genetics 43, 167-195, 2009
Muller's ratchet decreases fitness of a DNA-based microbe.
DI Andersson, D Hughes
Proceedings of the National Academy of Sciences 93 (2), 906-907, 1996
Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms
D Hughes, DI Andersson
Nature Reviews Genetics 16 (8), 459-471, 2015
Establishment of a Superficial Skin Infection Model in Mice by Using Staphylococcus aureus and Streptococcus pyogenes
E Kugelberg, T Norström, TK Petersen, T Duvold, DI Andersson, ...
Antimicrobial agents and chemotherapy 49 (8), 3435-3441, 2005
Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site
M Laurberg, O Kristensen, K Martemyanov, AT Gudkov, I Nagaev, ...
Journal of molecular biology 303 (4), 593-603, 2000
Limitations of translational accuracy
CG Kurland, D Hughes, M Ehrenberg
Escherichia coli and Salmonella, 979-1004, 1996
Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium
J Björkman, P Samuelsson, DI Andersson, D Hughes
Molecular microbiology 31 (1), 53-58, 1999
Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration
SK Olofsson, LL Marcusson, P Komp Lindgren, D Hughes, O Cars
Journal of Antimicrobial Chemotherapy 57 (6), 1116-1121, 2006
Biological Cost of Single and Multiple Norfloxacin Resistance Mutations in Escherichia coli Implicated in Urinary Tract Infections
PK Lindgren, LL Marcusson, D Sandvang, N Frimodt-Møller, D Hughes
Antimicrobial agents and chemotherapy 49 (6), 2343-2351, 2005
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