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Jon M Wigginton
Jon M Wigginton
President, Research and Developmen, Bright Peak Therapeutics
Verified email at brightpeaktx.com - Homepage
Title
Cited by
Cited by
Year
Safety, activity, and immune correlates of anti–PD-1 antibody in cancer
SL Topalian, FS Hodi, JR Brahmer, SN Gettinger, DC Smith, ...
New England Journal of Medicine 366 (26), 2443-2454, 2012
136942012
Safety, activity, and immune correlates of anti–PD-1 antibody in cancer
SL Topalian, FS Hodi, JR Brahmer, SN Gettinger, DC Smith, ...
New England Journal of Medicine 366 (26), 2443-2454, 2012
136942012
Safety and activity of anti–PD-L1 antibody in patients with advanced cancer
JR Brahmer, SS Tykodi, LQM Chow, WJ Hwu, SL Topalian, P Hwu, ...
New England Journal of Medicine 366 (26), 2455-2465, 2012
87382012
Nivolumab plus ipilimumab in advanced melanoma
JD Wolchok, H Kluger, MK Callahan, MA Postow, NA Rizvi, AM Lesokhin, ...
New England Journal of Medicine 369 (2), 122-133, 2013
49702013
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
SL Topalian, M Sznol, DF McDermott, HM Kluger, RD Carvajal, ...
Journal of clinical oncology 32 (10), 1020, 2014
26572014
Overall survival and long-term safety of nivolumab (anti–programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non–small-cell lung cancer
SN Gettinger, L Horn, L Gandhi, DR Spigel, SJ Antonia, NA Rizvi, ...
Journal of clinical oncology 33 (18), 2004, 2015
12812015
Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab
DF McDermott, CG Drake, M Sznol, TK Choueiri, JD Powderly, DC Smith, ...
Journal of clinical oncology 33 (18), 2013, 2015
4582015
Combination immunotherapy: a road map
PA Ott, FS Hodi, HL Kaufman, JM Wigginton, JD Wolchok
Journal for immunotherapy of cancer 5, 1-15, 2017
3682017
The C3 (1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma
JE Green, MA Shibata, K Yoshidome, M Liu, C Jorcyk, MR Anver, ...
Oncogene 19 (8), 1020-1027, 2000
3022000
Immunotherapy of cancer by IL-12-based cytokine combinations
JM Weiss, JJ Subleski, JM Wigginton, RH Wiltrout
Expert opinion on biological therapy 7 (11), 1705-1721, 2007
2832007
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy
S Gnjatic, V Bronte, LR Brunet, MO Butler, ML Disis, J Galon, ...
Journal for immunotherapy of cancer 5, 1-18, 2017
2282017
IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: role for CD8+ T cells
R Salcedo, JK Stauffer, E Lincoln, TC Back, JA Hixon, C Hahn, ...
The Journal of Immunology 173 (12), 7170-7182, 2004
2152004
Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary
R Gorlick, P Anderson, I Andrulis, C Arndt, GP Beardsley, M Bernstein, ...
Clinical Cancer Research 9 (15), 5442-5453, 2003
2062003
Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma
JM Wigginton, KL Komschlies, TC Back, JL Franco, MJ Brunda, ...
JNCI: Journal of the National Cancer Institute 88 (1), 38-43, 1996
1971996
IFN-γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy
JM Wigginton, E Gruys, L Geiselhart, J Subleski, KL Komschlies, JW Park, ...
The Journal of clinical investigation 108 (1), 51-62, 2001
1902001
Defining the critical hurdles in cancer immunotherapy
BA Fox, DJ Schendel, LH Butterfield, S Aamdal, JP Allison, PA Ascierto, ...
Journal of translational medicine 9, 1-15, 2011
1872011
Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22–05): A single-arm, phase 1b–2 trial
DVT Catenacci, YK Kang, H Park, HE Uronis, KW Lee, MCH Ng, ...
The lancet oncology 21 (8), 1066-1076, 2020
1602020
Anti‐tumour synergy of cytotoxic chemotherapy and anti‐CD40 plus CpG‐ODN immunotherapy through repolarization of tumour‐associated macrophages
IN Buhtoiarov, PM Sondel, JM Wigginton, TN Buhtoiarova, EM Yanke, ...
Immunology 132 (2), 226-239, 2011
1532011
Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
JP Cogswell, SM Goldberg, AK Gupta, M Jure-Kunkel, XT Wang, ...
US Patent 9,856,320, 2018
1412018
Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma …
R Salcedo, JA Hixon, JK Stauffer, R Jalah, AD Brooks, T Khan, RM Dai, ...
The Journal of Immunology 182 (7), 4328-4338, 2009
1252009
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