Frank Heppner
Frank Heppner
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DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
Immune attack: the role of inflammation in Alzheimer disease
FL Heppner, RM Ransohoff, B Becher
Nature Reviews Neuroscience 16 (6), 358-372, 2015
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases
S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ...
Immunity 47 (3), 566-581. e9, 2017
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
J Meinhardt, J Radke, C Dittmayer, J Franz, C Thomas, R Mothes, M Laue, ...
Nature neuroscience 24 (2), 168-175, 2021
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
M Greter, FL Heppner, MP Lemos, BM Odermatt, N Goebels, T Laufer, ...
Nature medicine 11 (3), 328-334, 2005
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration
T Buch, FL Heppner, C Tertilt, TJAJ Heinen, M Kremer, FT Wunderlich, ...
Nature methods 2 (6), 419-426, 2005
High-dimensional single-cell mapping of central nervous system immune cells reveals distinct myeloid subsets in health, aging, and disease
D Mrdjen, A Pavlovic, FJ Hartmann, B Schreiner, SG Utz, BP Leung, ...
Immunity 48 (2), 380-395. e6, 2018
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
FL Heppner, M Greter, D Marino, J Falsig, G Raivich, N Hövelmeyer, ...
Nature medicine 11 (2), 146-152, 2005
Stem cell–related “self-renewal” signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
A Murat, E Migliavacca, T Gorlia, WL Lambiv, T Shay, MF Hamou, ...
Journal of clinical oncology 26 (18), 3015-3024, 2008
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
SM Lehmann, C Krüger, B Park, K Derkow, K Rosenberger, J Baumgart, ...
Nature neuroscience 15 (6), 827-835, 2012
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: Quantitative in vivo imaging of microglia as a measure of disease activity
RB Banati, J Newcombe, RN Gunn, A Cagnin, F Turkheimer, F Heppner, ...
Brain 123 (11), 2321-2337, 2000
Microglia states and nomenclature: A field at its crossroads
RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ...
Neuron 110 (21), 3458-3483, 2022
Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice
S Pantelyushin, S Haak, B Ingold, P Kulig, FL Heppner, AA Navarini, ...
The Journal of clinical investigation 122 (6), 2252-2256, 2012
Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology
G Krabbe, A Halle, V Matyash, JL Rinnenthal, GD Eom, U Bernhardt, ...
PloS one 8 (4), e60921, 2013
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice
S Haak, AL Croxford, K Kreymborg, FL Heppner, S Pouly, B Becher, ...
The Journal of clinical investigation 119 (1), 61-69, 2009
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
SA Grathwohl, RE Kälin, T Bolmont, S Prokop, G Winkelmann, SA Kaeser, ...
Nature neuroscience 12 (11), 1361-1363, 2009
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline
J Vom Berg, S Prokop, KR Miller, J Obst, RE Kälin, I Lopategui-Cabezas, ...
Nature medicine 18 (12), 1812-1819, 2012
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
FL Heppner, C Musahl, I Arrighi, MA Klein, T Rülicke, B Oesch, ...
Science 294 (5540), 178-182, 2001
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
DS Markovic, K Vinnakota, S Chirasani, M Synowitz, H Raguet, K Stock, ...
Proceedings of the National Academy of Sciences 106 (30), 12530-12535, 2009
IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis
K Kreymborg, R Etzensperger, L Dumoutier, S Haak, A Rebollo, T Buch, ...
The Journal of Immunology 179 (12), 8098-8104, 2007
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