| ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor … JJ Donkin, S Stukas, V Hirsch-Reinshagen, D Namjoshi, A Wilkinson, ... Journal of Biological Chemistry 285 (44), 34144-34154, 2010 | 240 | 2010 |
| Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury DR Namjoshi, WH Cheng, KA McInnes, KM Martens, M Carr, A Wilkinson, ... Molecular neurodegeneration 9, 1-18, 2014 | 191 | 2014 |
| Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes M Valenza, V Leoni, JM Karasinska, L Petricca, J Fan, J Carroll, ... Journal of Neuroscience 30 (32), 10844-10850, 2010 | 170 | 2010 |
| Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ... Journal of Neuroscience 29 (11), 3579-3589, 2009 | 157 | 2009 |
| Greasing the wheels of Aβ clearance in Alzheimer's disease: the role of lipids and apolipoprotein E J Fan, J Donkin, C Wellington Biofactors 35 (3), 239-248, 2009 | 123 | 2009 |
| HDL from an Alzheimer's disease perspective EB Button, J Robert, TM Caffrey, J Fan, W Zhao, CL Wellington Current opinion in lipidology 30 (3), 224-234, 2019 | 97 | 2019 |
| Intravenously injected human apolipoprotein A‐I rapidly enters the central nervous system via the choroid plexus S Stukas, J Robert, M Lee, I Kulic, M Carr, K Tourigny, J Fan, D Namjoshi, ... Journal of the American Heart Association 3 (6), e001156, 2014 | 95 | 2014 |
| Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice J Robert, S Stukas, E Button, WH Cheng, M Lee, J Fan, A Wilkinson, ... Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (5 …, 2016 | 87 | 2016 |
| ABCA1 influences neuroinflammation and neuronal death JM Karasinska, W de Haan, S Franciosi, P Ruddle, J Fan, JK Kruit, ... Neurobiology of disease 54, 445-455, 2013 | 78 | 2013 |
| LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins V Hirsch-Reinshagen, J Donkin, S Stukas, J Chan, A Wilkinson, J Fan, ... Journal of lipid research 50 (5), 885-893, 2009 | 77 | 2009 |
| ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo BL Burgess, PF Parkinson, MM Racke, V Hirsch-Reinshagen, J Fan, ... Journal of lipid research 49 (6), 1254-1267, 2008 | 70 | 2008 |
| The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E DR Namjoshi, G Martin, J Donkin, A Wilkinson, S Stukas, J Fan, M Carr, ... PloS one 8 (1), e53529, 2013 | 65 | 2013 |
| Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice B Burgess, K Naus, J Chan, V Hirsch-Reinshagen, G Tansley, L Matzke, ... Arteriosclerosis, thrombosis, and vascular biology 28 (10), 1731-1737, 2008 | 64 | 2008 |
| Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway J Fan, RQ Zhao, C Parro, W Zhao, HY Chou, J Robert, TZ Deeb, ... Journal of lipid research 59 (5), 830-842, 2018 | 47 | 2018 |
| ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP … EB Button, GK Boyce, A Wilkinson, S Stukas, A Hayat, J Fan, ... Alzheimer's research & therapy 11, 1-18, 2019 | 43 | 2019 |
| Hormonal modulators of glial ABCA1 and apoE levels [S] J Fan, Y Shimizu, J Chan, A Wilkinson, A Ito, P Tontonoz, E Dullaghan, ... Journal of lipid research 54 (11), 3139-3150, 2013 | 31 | 2013 |
| An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia J Fan, S Stukas, C Wong, J Chan, S May, N DeValle, ... Journal of Lipid Research 52 (9), 1605-1616, 2011 | 29 | 2011 |
| Identification of a chrysanthemic ester as an apolipoprotein E inducer in astrocytes J Fan, S Zareyan, W Zhao, Y Shimizu, TA Pfeifer, JH Tak, MB Isman, ... PloS one 11 (9), e0162384, 2016 | 24 | 2016 |
| Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-β peptide levels in vivo V Hirsch-Reinshagen, JY Chan, A Wilkinson, T Tanaka, J Fan, G Ou, ... Journal of lipid research 48 (4), 914-923, 2007 | 20 | 2007 |
| Axl receptor tyrosine kinase is a regulator of apolipoprotein E W Zhao, J Fan, I Kulic, C Koh, A Clark, J Meuller, O Engkvist, S Barichievy, ... Molecular Brain 13, 1-13, 2020 | 12 | 2020 |
