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Helmut Grasberger
Helmut Grasberger
Verified email at umich.edu
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Cited by
Cited by
Year
Identification of the maturation factor for dual oxidase: evolution of an eukaryotic operon equivalent
H Grasberger, S Refetoff
Journal of Biological Chemistry 281 (27), 18269-18272, 2006
3792006
Genetic causes of congenital hypothyroidism due to dyshormonogenesis
H Grasberger, S Refetoff
Current opinion in pediatrics 23 (4), 421-428, 2011
2522011
Activation of dual oxidases Duox1 and Duox2
S Rigutto, C Hoste, H Grasberger, M Milenkovic, D Communi, JE Dumont, ...
Journal of Biological Chemistry 284 (11), 6725-6734, 2009
2452009
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
S Lipinski, A Till, C Sina, A Arlt, H Grasberger, S Schreiber, P Rosenstiel
Journal of cell science 122 (19), 3522-3530, 2009
2212009
Functional characterization of inflammatory bowel disease–associated gut dysbiosis in gnotobiotic mice
H Nagao-Kitamoto, AB Shreiner, MG Gillilland III, S Kitamoto, C Ishii, ...
Cellular and molecular gastroenterology and hepatology 2 (4), 468-481, 2016
2202016
Biallelic Inactivation of the Dual Oxidase Maturation Factor 2 (DUOXA2) Gene as a Novel Cause of Congenital Hypothyroidism
I Zamproni, H Grasberger, F Cortinovis, MC Vigone, G Chiumello, S Mora, ...
The Journal of Clinical Endocrinology & Metabolism 93 (2), 605-610, 2008
2002008
Increased expression of DUOX2 is an epithelial response to mucosal dysbiosis required for immune homeostasis in mouse intestine
H Grasberger, J Gao, H Nagao-Kitamoto, S Kitamoto, M Zhang, ...
Gastroenterology 149 (7), 1849-1859, 2015
1302015
Defects of thyroidal hydrogen peroxide generation in congenital hypothyroidism
H Grasberger
Molecular and cellular endocrinology 322 (1-2), 99-106, 2010
1232010
A Familial Thyrotropin (TSH) Receptor Mutation Provides in Vivo Evidence that the Inositol Phosphates/Ca2+ Cascade Mediates TSH Action on Thyroid Hormone …
H Grasberger, J Van Sande, A Hag-Dahood Mahameed, ...
The journal of clinical endocrinology & metabolism 92 (7), 2816-2820, 2007
1212007
Dietary l-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut
S Kitamoto, CJ Alteri, M Rodrigues, H Nagao-Kitamoto, K Sugihara, ...
Nature Microbiology 5 (1), 116-125, 2020
1082020
Dual oxidases control release of hydrogen peroxide by the gastric epithelium to prevent Helicobacter felis infection and inflammation in mice
H Grasberger, M El–Zaatari, DT Dang, JL Merchant
Gastroenterology 145 (5), 1045-1054, 2013
1072013
Mice deficient in dual oxidase maturation factors are severely hypothyroid
H Grasberger, X De Deken, OB Mayo, H Raad, M Weiss, XH Liao, ...
Molecular endocrinology 26 (3), 481-492, 2012
962012
Missense Mutations of Dual Oxidase 2 (DUOX2) Implicated in Congenital Hypothyroidism Have Impaired Trafficking in Cells Reconstituted with DUOX2 Maturation …
H Grasberger, X De Deken, F Miot, J Pohlenz, S Refetoff
Molecular Endocrinology 21 (6), 1408-1421, 2007
962007
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity
H Grasberger, U Ringkananont, P LeFrancois, M Abramowicz, G Vassart, ...
Molecular endocrinology 19 (7), 1779-1791, 2005
952005
The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expression.
S Hofmann, H Grasberger, P Jung, M Bidlingmaier, J Vlotides, ...
European journal of medical research 7 (4), 171-176, 2002
912002
A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 …
I Hulur, P Hermanns, C Nestoris, S Heger, S Refetoff, J Pohlenz, ...
The Journal of Clinical Endocrinology & Metabolism 96 (5), E841-E845, 2011
732011
Dual oxidase regulates neutrophil recruitment in allergic airways
S Chang, A Linderholm, L Franzi, N Kenyon, H Grasberger, R Harper
Free Radical Biology and Medicine 65, 38-46, 2013
702013
Tryptophan catabolism restricts IFN-γ–expressing neutrophils and Clostridium difficile immunopathology
M El-Zaatari, YM Chang, M Zhang, M Franz, A Shreiner, AJ McDermott, ...
The Journal of Immunology 193 (2), 807-816, 2014
642014
Genetic complexity of Crohn’s disease in two large Ashkenazi Jewish families
AP Levine, N Pontikos, ER Schiff, L Jostins, D Speed, LB Lovat, JC Barrett, ...
Gastroenterology 151 (4), 698-709, 2016
622016
Loss-of-function mutations in the thyrotropin receptor gene as a major determinant of hyperthyrotropinemia in a consanguineous community
Y Tenenbaum-Rakover, H Grasberger, S Mamanasiri, U Ringkananont, ...
The Journal of Clinical Endocrinology & Metabolism 94 (5), 1706-1712, 2009
542009
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