Specific recognition of cruciform DNA by nuclear protein HMG1 ME Bianchi, M Beltrame, G Paonessa Science 243 (4894), 1056-1059, 1989 | 758 | 1989 |
Two distinct and independent sites on IL‐6 trigger gp 130 dimer formation and signalling. G Paonessa, R Graziani, A De Serio, R Savino, L Ciapponi, A Lahm, ... The EMBO journal 14 (9), 1942-1951, 1995 | 343 | 1995 |
Isolation of human glucose-6-pbosphate debydrogenase (G6PD) cDNA clones: primary structure of the protein and unusual 5'non-coding region MG Persico, G Viglietto, G Martini, D Toniolo, G Paonessa, C Moscatelli, ... Nucleic acids research 14 (6), 2511-2522, 1986 | 336 | 1986 |
Structural analysis of the X‐linked gene encoding human glucose 6‐phosphate dehydrogenase. G Martini, D Toniolo, T Vulliamy, L Luzzatto, R Dono, G Viglietto, ... The EMBO journal 5 (8), 1849-1855, 1986 | 292 | 1986 |
Purification of a NF1‐like DNA‐binding protein from rat liver and cloning of the corresponding cDNA. G Paonessa, F Gounari, R Frank, R Cortese The EMBO journal 7 (10), 3115-3123, 1988 | 282 | 1988 |
Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance I Gloaguen, P Costa, A Demartis, D Lazzaro, A Di Marco, R Graziani, ... Proceedings of the National Academy of Sciences 94 (12), 6456-6461, 1997 | 279 | 1997 |
Two distinct factors interact with the promoter regions of several liver‐specific genes. EM Hardon, M Frain, G Paonessa, R Cortese The EMBO Journal 7 (6), 1711-1719, 1988 | 256 | 1988 |
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein MT Catanese, R Graziani, T von Hahn, M Moreau, T Huby, G Paonessa, ... Journal of virology 81 (15), 8063-8071, 2007 | 204 | 2007 |
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants MT Catanese, H Ansuini, R Graziani, T Huby, M Moreau, JK Ball, ... Journal of virology 84 (1), 34-43, 2010 | 199 | 2010 |
Cis‐and trans‐acting elements responsible for the cell‐specific expression of the human alpha 1‐antitrypsin gene. V De Simone, G Ciliberto, E Hardon, G Paonessa, F Palla, L Lundberg, ... The EMBO journal 6 (9), 2759-2766, 1987 | 193 | 1987 |
Generation of interleukin‐6 receptor antagonists by molecular‐modeling guided mutagenesis of residues important for gp130 activation. R Savino, A Lahm, AL Salvati, L Ciapponi, E Sporeno, S Altamura, ... The EMBO journal 13 (6), 1357-1367, 1994 | 168 | 1994 |
In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor C Trozzi, L Bartholomew, A Ceccacci, G Biasiol, L Pacini, S Altamura, ... Journal of virology 77 (6), 3669-3679, 2003 | 161 | 2003 |
Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus … F Benigni, G Fantuzzi, S Sacco, M Sironi, P Pozzi, CA Dinarello, JD Sipe, ... | 156 | 1996 |
Human interleukin-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells E Sporeno, R Savino, L Ciapponi, G Paonessa, A Cabibbo, A Lahm, ... | 136 | 1996 |
Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase S Harper, S Avolio, B Pacini, M Di Filippo, S Altamura, L Tomei, ... Journal of medicinal chemistry 48 (14), 4547-4557, 2005 | 133 | 2005 |
Persistent replication of hepatitis C virus replicons expressing the β-lactamase reporter in subpopulations of highly permissive Huh7 cells EM Murray, JA Grobler, EJ Markel, MF Pagnoni, G Paonessa, AJ Simon, ... Journal of virology 77 (5), 2928-2935, 2003 | 104 | 2003 |
Nucleotide sequence of rat liver HMG1 cDNA. G Paonessa, R Frank, R Cortese Nucleic acids research 15 (21), 9077, 1987 | 98 | 1987 |
Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions H DAHMEN, U HORSTEN, A KÜSTER, Y JACQUES, S MINVIELLE, ... Biochemical Journal 331 (3), 695-702, 1998 | 93 | 1998 |
Oncostatin M binds directly to gp130 and behaves as interleukin-6 antagonist on a cell line expressing gp130 but lacking functional oncostatin M receptors E Sporeno, G Paonessa, AL Salvati, R Graziani, P Delmastro, G Ciliberto, ... Journal of Biological Chemistry 269 (15), 10991-10995, 1994 | 83 | 1994 |
Review HCV Antiviral Resistance: The Impact of in vitro Studies on the Development of Antiviral Agents Targeting the Viral NS5B Polymerase L Tomei, S Altamura, G Paonessa, R De Francesco, G Migliaccio Antiviral chemistry and chemotherapy 16 (4), 225-245, 2005 | 82 | 2005 |