Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans H McShane, AA Pathan, CR Sander, SM Keating, SC Gilbert, K Huygen, ... Nature medicine 10 (11), 1240-1244, 2004 | 784 | 2004 |
Upregulation of TGF-β, FOXP3, and CD4+ CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection M Walther, JE Tongren, L Andrews, D Korbel, E King, H Fletcher, ... Immunity 23 (3), 287-296, 2005 | 483 | 2005 |
Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA− NP+ M1 TK Berthoud, M Hamill, PJ Lillie, L Hwenda, KA Collins, KJ Ewer, A Milicic, ... Clinical infectious diseases 52 (1), 1-7, 2011 | 356 | 2011 |
T-cell activation is an immune correlate of risk in BCG vaccinated infants HA Fletcher, MA Snowden, B Landry, W Rida, I Satti, SA Harris, ... Nature communications 7 (1), 11290, 2016 | 309 | 2016 |
Recognition of Stage-Specific Mycobacterial Antigens Differentiates between Acute and Latent Infections with Mycobacterium tuberculosis A Demissie, EMS Leyten, M Abebe, L Wassie, A Aseffa, G Abate, ... Clinical and vaccine immunology 13 (2), 179-186, 2006 | 274 | 2006 |
Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4δ2 A Demissie, M Abebe, A Aseffa, G Rook, H Fletcher, A Zumla, K Weldingh, ... The Journal of Immunology 172 (11), 6938-6943, 2004 | 256 | 2004 |
Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa T Hawkridge, TJ Scriba, S Gelderbloem, E Smit, M Tameris, S Moyo, ... The Journal of infectious diseases 198 (4), 544-552, 2008 | 223 | 2008 |
COVID-19 as a global challenge: towards an inclusive and sustainable future H Lambert, J Gupte, H Fletcher, L Hammond, N Lowe, M Pelling, N Raina, ... The Lancet Planetary Health 4 (8), e312-e314, 2020 | 219 | 2020 |
Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials H McShane, AA Pathan, CR Sander, NP Goonetilleke, HA Fletcher, ... Tuberculosis 85 (1-2), 47-52, 2005 | 177 | 2005 |
Human immunology of tuberculosis TJ Scriba, AK Coussens, HA Fletcher Microbiology spectrum 5 (1), 10.1128/microbiolspec. tbtb2-0016-2016, 2017 | 157 | 2017 |
Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study JR Andrews, E Nemes, M Tameris, BS Landry, H Mahomed, JB McClain, ... The lancet Respiratory medicine 5 (4), 282-290, 2017 | 147 | 2017 |
Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy V Naranbhai, AVS Hill, SS Abdool Karim, K Naidoo, Q Abdool Karim, ... The Journal of infectious diseases 209 (4), 500-509, 2014 | 145 | 2014 |
Association of human antibodies to arabinomannan with enhanced mycobacterial opsonophagocytosis and intracellular growth reduction T Chen, C Blanc, AZ Eder, R Prados-Rosales, ACO Souza, RS Kim, ... The Journal of infectious diseases 214 (2), 300-310, 2016 | 138 | 2016 |
Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians HA Fletcher, HD Donoghue, G Michael Taylor, AGM van der Zanden, ... Microbiology 149 (1), 143-151, 2003 | 137 | 2003 |
TB vaccine development and the End TB Strategy: importance and current status HA Fletcher, L Schrager Transactions of the Royal Society of Tropical Medicine and Hygiene 110 (4 …, 2016 | 126 | 2016 |
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses A Ogbe, B Kronsteiner, DT Skelly, M Pace, A Brown, E Adland, K Adair, ... Nature communications 12 (1), 2055, 2021 | 125 | 2021 |
Perspectives on advances in tuberculosis diagnostics, drugs, and vaccines M Schito, GB Migliori, HA Fletcher, R McNerney, R Centis, L D'Ambrosio, ... Clinical infectious diseases 61 (suppl_3), S102-S118, 2015 | 125 | 2015 |
A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis SA Joosten, HA Fletcher, THM Ottenhoff PloS one 8 (9), e73230, 2013 | 121 | 2013 |
Sensitivity of IFN-γ release assay to detect latent tuberculosis infection is retained in HIV-infected patients but dependent on HIV/AIDS progression F Karam, F Mbow, H Fletcher, CS Senghor, KD Coulibaly, AM LeFevre, ... PLoS One 3 (1), e1441, 2008 | 120 | 2008 |
Progress and challenges in TB vaccine development G Voss, D Casimiro, O Neyrolles, A Williams, SHE Kaufmann, H McShane, ... F1000Research 7, 2018 | 117 | 2018 |