Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents AN Matralis, MG Katselou, A Nikitakis, AP Kourounakis Journal of medicinal chemistry 54 (15), 5583-5591, 2011 | 76 | 2011 |
Human isoprenoid synthase enzymes as therapeutic targets J Park, AN Matralis, AM Berghuis, YS Tsantrizos Frontiers in chemistry 2, 50, 2014 | 63 | 2014 |
Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: Exploiting phenothiazine’s strong antioxidant activity AN Matralis, AP Kourounakis Journal of medicinal chemistry 57 (6), 2568-2581, 2014 | 58 | 2014 |
Development and therapeutic potential of autotaxin small molecule inhibitors: From bench to advanced clinical trials AN Matralis, A Afantitis, V Aidinis Medicinal research reviews 39 (3), 976-1013, 2019 | 48 | 2019 |
Multi-target drug design approaches for multifactorial diseases: From neurodegenerative to cardiovascular applications MG Katselou, AN Matralis, AP Kourounakis Current medicinal chemistry 21 (24), 2743-2787, 2014 | 47 | 2014 |
Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents A P. Kourounakis, M G. Katselou, A N. Matralis, E M. Ladopoulou, ... Current medicinal chemistry 18 (29), 4418-4439, 2011 | 42 | 2011 |
Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution EM Ladopoulou, AN Matralis, A Nikitakis, AP Kourounakis Bioorganic & medicinal chemistry 23 (21), 7015-7023, 2015 | 39 | 2015 |
Design of more potent squalene synthase inhibitors with multiple activities AP Kourounakis, AN Matralis, A Nikitakis Bioorganic & medicinal chemistry 18 (21), 7402-7412, 2010 | 39 | 2010 |
Commonalities between ARDS, pulmonary fibrosis and COVID-19: the potential of autotaxin as a therapeutic target K Ntatsoulis, T Karampitsakos, E Tsitoura, EA Stylianaki, AN Matralis, ... Frontiers in Immunology 12, 687397, 2021 | 36 | 2021 |
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites AN Matralis, A Malik, M Penzo, I Moreno, MJ Almela, I Camino, B Crespo, ... Journal of medicinal chemistry 62 (20), 9217-9235, 2019 | 34 | 2019 |
Antioxidant Activity of Newly Synthesized 2, 7‐Diazaphenothiazines B Morak‐Młodawska, K Pluta, AN Matralis, AP Kourounakis Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2010 | 32 | 2010 |
Pharmacophore mapping of thienopyrimidine-based monophosphonate (ThP-MP) inhibitors of the human farnesyl pyrophosphate synthase J Park, CY Leung, AN Matralis, CM Lacbay, M Tsakos, ... Journal of Medicinal Chemistry 60 (5), 2119-2134, 2017 | 30 | 2017 |
Water-Soluble Stoichiometric Polyelectrolyte Complexes Based on Cationic Comb-Type Copolymers A Matralis, M Sotiropoulou, G Bokias, G Staikos Macromolecular Chemistry and Physics 207 (12), 1018-1025, 2005 | 29 | 2005 |
New Multifunctional Di-tert-butylphenoloctahydro(pyrido/benz)oxazine Derivatives with Antioxidant, Antihyperlipidemic, and Antidiabetic Action E Ladopoulou, AN Matralis, AP Kourounakis Journal of medicinal chemistry 56 (8), 3330-3338, 2013 | 25 | 2013 |
Targeting the malaria parasite cGMP-dependent protein kinase to develop new drugs DA Baker, AN Matralis, SA Osborne, JM Large, M Penzo Frontiers in Microbiology 11, 602803, 2020 | 20 | 2020 |
Molecular tools that block maturation of the nuclear lamin A and decelerate cancer cell migration AN Matralis, D Xanthopoulos, G Huot, S Lopes-Paciencia, C Cole, ... Bioorganic & Medicinal Chemistry 26 (20), 5547-5554, 2018 | 19 | 2018 |
Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity MG Katselou, AN Matralis, AP Kourounakis European Journal of Medicinal Chemistry 138, 748-760, 2017 | 17 | 2017 |
Optimizing the pharmacological profile of new bifunctional antihyperlipidemic/antioxidant morpholine derivatives AN Matralis, AP Kourounakis ACS Medicinal Chemistry Letters 10 (1), 98-104, 2018 | 15 | 2018 |
Evaluation of two novel antioxidants with differential effects on curcumin-induced apoptosis in C2 skeletal myoblasts; involvement of JNKs M Peleli, IK Aggeli, AN Matralis, AP Kourounakis, I Beis, C Gaitanaki Bioorganic & Medicinal Chemistry 23 (3), 390-400, 2015 | 14 | 2015 |
Structure-based discovery of novel chemical classes of autotaxin inhibitors C Magkrioti, E Kaffe, EA Stylianaki, C Sidahmet, G Melagraki, A Afantitis, ... International Journal of Molecular Sciences 21 (19), 7002, 2020 | 9 | 2020 |