Antony W Oliver

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Laurence PearlProfessor of Structural Biology, University of SussexVerified email at sussex.ac.uk
Matthew DayLecturer in Biochemistry, SBBS, Queen Mary University of LondonVerified email at qmul.ac.uk
Michelle GarrettProfessor of Cancer TherapeuticsVerified email at kent.ac.uk
Stuart RultenUniversity of SussexVerified email at sussex.ac.uk
Simon E WardCardiff UniversityVerified email at cardiff.ac.uk
Gabrielle GrundyResearch Fellow, Department of Molecular & Clinical Cancer Medicine, ISMIB, University of LiverpoolVerified email at liverpool.ac.uk
Geoff KnealeProfessor of Biomolecular Science, Portsmouth UniversityVerified email at port.ac.uk
Victoria AndersonAssociate Director, AdaptimmuneVerified email at adaptimmune.com
Luis Mariano PoloIHEM-CONICET-UNCUYOVerified email at mendoza-conicet.gob.ar
Stefan KnappUniversity of FrankfurtVerified email at pharmchem.uni-frankfurt.de
Christopher LordProfessor of Cancer Genomics, Institute of Cancer Research, London, UKVerified email at icr.ac.uk
Andrew N. BlackfordAssociate Professor, University of OxfordVerified email at imm.ox.ac.uk
Christopher P WardlawMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Andreas LadurnerChair of Physiological Chemistry, LMU Munich; Founder, Managing Director and CSO, Eisbach Bio GmbHVerified email at med.lmu.de
Marek KozlowskiThe International Max Planck Research School for Molecular and Cellular Life Sciences, Martinsried, GermanyVerified email at med.lmu.de
Gyula TiminszkyBiological Research Centre of the Hungarian Academy of SciencesVerified email at brc.mta.hu
Dr. Thomas EtheridgeResearch Fellow, Genome Damage and Stability CentreVerified email at sussex.ac.uk
Robert BaldockUniversity of PortsmouthVerified email at port.ac.uk
Fernando GarcesCEO @ BioGlyph, Inc.Verified email at bioglyph.app
Helfrid HocheggerGDSC, University of SussexVerified email at sussex.ac.uk

Antony W Oliver

Principal Research Fellow, University of Sussex

Verified email at sussex.ac.uk - Homepage

Structural Biology DNA Repair


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The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks AAE Ali, G Timinszky, R Arribas-Bosacoma, M Kozlowski, PO Hassa, ... Nature structural & molecular biology 19 (7), 685-692, 2012	339	2012
Structural basis for recruitment of BRCA2 by PALB2 AW Oliver, S Swift, CJ Lord, A Ashworth, LH Pearl EMBO reports 10 (9), 990-996, 2009	222	2009
Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans D Boos, L Sanchez-Pulido, M Rappas, LH Pearl, AW Oliver, CP Ponting, ... Current Biology 21 (13), 1152-1157, 2011	192	2011
Activation segment dimerization: a mechanism for kinase autophosphorylation of non‐consensus sites ACW Pike, P Rellos, FH Niesen, A Turnbull, AW Oliver, SA Parker, ... The EMBO journal 27 (4), 704-714, 2008	185	2008
Crystal structure of the catalytic fragment of murine poly (ADP‐ribose) polymerase‐2 AW Oliver, JC Amé, SM Roe, V Good, G de Murcia, LH Pearl Nucleic acids research 32 (2), 456-464, 2004	185	2004
APLF promotes the assembly and activity of non‐homologous end joining protein complexes GJ Grundy, SL Rulten, Z Zeng, R Arribas‐Bosacoma, N Iles, K Manley, ... The EMBO journal 32 (1), 112-125, 2013	182	2013
Trans‐activation of the DNA‐damage signalling protein kinase Chk2 by T‐loop exchange AW Oliver, A Paul, KJ Boxall, SE Barrie, GW Aherne, MD Garrett, ... The EMBO journal 25 (13), 3179-3190, 2006	160	2006
TopBP1: A BRCT-scaffold protein functioning in multiple cellular pathways CP Wardlaw, AM Carr, AW Oliver DNA repair 22, 165-174, 2014	133	2014
The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function C Breslin, P Hornyak, A Ridley, SL Rulten, H Hanzlikova, AW Oliver, ... Nucleic acids research 43 (14), 6934-6944, 2015	123	2015
MDC1 interacts with TOPBP1 to maintain chromosomal stability during mitosis PA Leimbacher, SE Jones, AMK Shorrocks, M de Marco Zompit, M Day, ... Molecular cell 74 (3), 571-583. e8, 2019	121	2019
CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors VE Anderson, MI Walton, PD Eve, KJ Boxall, L Antoni, JJ Caldwell, ... Cancer research 71 (2), 463-472, 2011	120	2011
Activation segment exchange: a common mechanism of kinase autophosphorylation? AW Oliver, S Knapp, LH Pearl Trends in biochemical sciences 32 (8), 351-356, 2007	109	2007
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity JR Becker, R Cuella-Martin, M Barazas, R Liu, C Oliveira, AW Oliver, ... Nature communications 9 (1), 5406, 2018	106	2018
Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA K Zabrady, M Adamus, L Vondrova, C Liao, H Skoupilova, M Novakova, ... Nucleic acids research 44 (3), 1064-1079, 2016	97	2016
Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease SN Van Der Crabben, MP Hennus, GA McGregor, DI Ritter, ... The Journal of clinical investigation 126 (8), 2881-2892, 2016	94	2016
Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1 M Rappas, AW Oliver, LH Pearl Nucleic acids research 39 (1), 313-324, 2011	89	2011
Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity AS Dore, ML Kilkenny, SA Jones, AW Oliver, SM Roe, SD Bell, LH Pearl Nucleic Acids Research 34 (16), 4515-4526, 2006	87	2006
PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B^Glu2 GJ Grundy, LM Polo, Z Zeng, SL Rulten, NC Hoch, P Paomephan, Y Xu, ... Nature communications 7 (1), 12404, 2016	84	2016
Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK AAE Ali, RM Jukes, LH Pearl, AW Oliver Nucleic acids research 37 (5), 1701-1712, 2009	84	2009
Specialized interfaces of Smc5/6 control hinge stability and DNA association A Alt, HQ Dang, OS Wells, LM Polo, MA Smith, GA McGregor, T Welte, ... Nature communications 8 (1), 14011, 2017	83	2017

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