Pui Kai Li
Pui Kai Li
Associate Professor, The Ohio State University
Verified email at
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Curcumin is a potent DNA hypomethylation agent
Z Liu, Z Xie, W Jones, RE Pavlovicz, S Liu, J Yu, P Li, J Lin, JR Fuchs, ...
Bioorganic & medicinal chemistry letters 19 (3), 706-709, 2009
Multi-targeted therapy of cancer by niclosamide: A new application for an old drug
Y Li, PK Li, MJ Roberts, RC Arend, RS Samant, DJ Buchsbaum
Cancer letters 349 (1), 8-14, 2014
STAT3 is necessary for proliferation and survival in colon cancer–initiating cells
L Lin, A Liu, Z Peng, HJ Lin, PK Li, C Li, J Lin
Cancer research 71 (23), 7226-7237, 2011
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy
M Sen, SM Thomas, S Kim, JI Yeh, RL Ferris, JT Johnson, U Duvvuri, ...
Cancer discovery 2 (8), 694-705, 2012
Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells
L Lin, B Hutzen, M Zuo, S Ball, S Deangelis, E Foust, B Pandit, MA Ihnat, ...
Cancer research 70 (6), 2445-2454, 2010
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells
L Lin, B Hutzen, PK Li, S Ball, M Zuo, S DeAngelis, E Foust, M Sobo, ...
Neoplasia 12 (1), 39-IN5, 2010
JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells
P Kroon, PA Berry, MJ Stower, G Rodrigues, VM Mann, M Simms, ...
Cancer research 73 (16), 5288-5298, 2013
Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells
Y Liu, PK Li, C Li, J Lin
Journal of Biological Chemistry 285 (35), 27429-27439, 2010
Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030
L Lin, Y Liu, H Li, PK Li, J Fuchs, H Shibata, Y Iwabuchi, J Lin
British journal of cancer 105 (2), 212-220, 2011
Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3
KF Chen, WT Tai, TH Liu, HP Huang, YC Lin, CW Shiau, PK Li, PJ Chen, ...
Clinical cancer research 16 (21), 5189-5199, 2010
Structure–activity relationship studies of curcumin analogues
JR Fuchs, B Pandit, D Bhasin, JP Etter, N Regan, D Abdelhamid, C Li, ...
Bioorganic & medicinal chemistry letters 19 (7), 2065-2069, 2009
Modulation of DNA methylation by a sesquiterpene lactone parthenolide
Z Liu, S Liu, Z Xie, RE Pavlovicz, J Wu, P Chen, J Aimiuwu, J Pang, ...
Journal of Pharmacology and Experimental Therapeutics 329 (2), 505-514, 2009
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells
L Lin, S Deangelis, E Foust, J Fuchs, C Li, PK Li, EB Schwartz, ...
Molecular cancer 9, 1-10, 2010
Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling
PA Agudelo-Garcia, JK De Jesus, SP Williams, MO Nowicki, EA Chiocca, ...
Neoplasia 13 (9), 831-IN22, 2011
Characterization of STAT3 activation and expression in canine and human osteosarcoma
SL Fossey, AT Liao, JK McCleese, MD Bear, J Lin, PK Li, WC Kisseberth, ...
BMC cancer 9, 1-15, 2009
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
MA Bill, JR Fuchs, C Li, J Yui, C Bakan, DM Benson, EB Schwartz, ...
Molecular cancer 9, 1-12, 2010
Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury
J Zhao, H Yu, Y Liu, SA Gibson, Z Yan, X Xu, A Gaggar, PK Li, C Li, S Wei, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (5 …, 2016
Design, synthesis, and studies of small molecule STAT3 inhibitors
D Bhasin, K Cisek, T Pandharkar, N Regan, C Li, B Pandit, J Lin, PK Li
Bioorganic & medicinal chemistry letters 18 (1), 391-395, 2008
Design and synthesis of Pfmrk inhibitors as potential antimalarial agents
Z Xiao, NC Waters, CL Woodard, Z Li, PK Li
Bioorganic & medicinal chemistry letters 11 (21), 2875-2878, 2001
LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
B Fuh, M Sobo, L Cen, D Josiah, B Hutzen, K Cisek, D Bhasin, N Regan, ...
British journal of cancer 100 (1), 106-112, 2009
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