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Rajasekaran Ganesan
Rajasekaran Ganesan
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy
Verified email at usc.edu
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Year
LL-37-derived short antimicrobial peptide KR-12-a5 and its d-amino acid substituted analogs with cell selectivity, anti-biofilm activity, synergistic effect with conventional …
EY Kim, G Rajasekaran, SY Shin
European journal of medicinal chemistry 136, 428-441, 2017
1032017
LL-37-derived membrane-active FK-13 analogs possessing cell selectivity, anti-biofilm activity and synergy with chloramphenicol and anti-inflammatory activity
G Rajasekaran, EY Kim, SY Shin
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (5), 722-733, 2017
922017
Pyrazole derived ultra-short antimicrobial peptidomimetics with potent anti-biofilm activity
M Ahn, P Gunasekaran, G Rajasekaran, EY Kim, SJ Lee, G Bang, K Cho, ...
European journal of medicinal chemistry 125, 551-564, 2017
732017
Antimicrobial and anti-inflammatory activities of chemokine CXCL14-derived antimicrobial peptide and its analogs
G Rajasekaran, SD Kumar, J Nam, D Jeon, Y Kim, CW Lee, IS Park, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1861 (1), 256-267, 2019
562019
DNA free energy-based promoter prediction and comparative analysis of Arabidopsis and rice genomes
C Morey, S Mookherjee, G Rajasekaran, M Bansal
Plant physiology 156 (3), 1300-1315, 2011
552011
Structural and Functional Assessment of mBjAMP1, an Antimicrobial Peptide from Branchiostoma japonicum, Revealed a Novel α-Hairpinin-like Scaffold with …
J Nam, H Yun, G Rajasekaran, SD Kumar, JI Kim, HJ Min, SY Shin, ...
Journal of Medicinal Chemistry 61 (24), 11101-11113, 2018
402018
Cationic amphipathic triazines with potent anti-bacterial, anti-inflammatory and anti-atopic dermatitis properties
P Gunasekaran, G Rajasekaran, EH Han, YH Chung, YJ Choi, YJ Yang, ...
Scientific Reports 9 (1), 1292, 2019
342019
Enhancement of the anti‐inflammatory activity of temporin‐1Tl‐derived antimicrobial peptides by tryptophan, arginine and lysine substitutions
G Rajasekaran, R Kamalakannan, SY Shin
Journal of Peptide Science 21 (10), 779-785, 2015
192015
The design of a cell-selective fowlicidin-1-derived peptide with both antimicrobial and anti-inflammatory activities
G Rajasekaran, SD Kumar, S Yang, SY Shin
European Journal of Medicinal Chemistry 182, 111623, 2019
182019
The stereochemical effect of SMAP-29 and SMAP-18 on bacterial selectivity, membrane interaction and anti-inflammatory activity
B Jacob, G Rajasekaran, EY Kim, IS Park, JK Bang, SY Shin
Amino Acids 48, 1241-1251, 2016
162016
Rattusin structure reveals a novel defensin scaffold formed by intermolecular disulfide exchanges
HJ Min, H Yun, S Ji, G Rajasekaran, JI Kim, JS Kim, SY Shin, CW Lee
Scientific Reports 7 (1), 45282, 2017
142017
Engineered cyclotides with potent broad in vitro and in vivo antimicrobial activity.
R Ganesan, MA Dughbaj, L Ramirez, S Beringer, TL Aboye, A Shekhtman, ...
Chem. Eur. J. (Easton), 2021
122021
Chemical synthesis of a potent antimicrobial peptide murepavadin using a tandem native chemical ligation/desulfurization reaction
D Chaudhuri, R Ganesan, A Vogelaar, MA Dughbaj, PM Beringer, ...
The Journal of organic chemistry 86 (21), 15242-15246, 2021
92021
Enhancement of Antibacterial Activity of Short Tryptophan-rich Antimicrobial Peptide Pac-525 by Replacing Trp with His (chx).
M Ahn, G Rajasekaran, P Gunasekaran, E kyoung Ryu, G Lee, JK Hyun, ...
Bulletin of the Korean Chemical Society 35 (9), 2014
52014
Improving Cell Selectivity of Fowlicidin‐1 by Swapping Residues between Pro‐7 and Tyr‐20
G Rajasekaran, SD Kumar, S Yang, SY Shin
Bulletin of the Korean Chemical Society 40 (5), 429-434, 2019
22019
Fowlicidin‐3 Analog with Improved Cell Selectivity Synthesized by Shifting a PXXP Motif from the N‐Terminus to a Central Position
G Rajasekaran, SY Shin
Bulletin of the Korean Chemical Society 39 (3), 287-293, 2018
22018
Resistance is futile: targeting multidrug-resistant bacteria with de novo Cys-rich cyclic polypeptides
A Mourenza, R Ganesan, JA Camarero
RSC Chemical Biology 4 (10), 722-735, 2023
12023
Cover Feature: Engineered Cyclotides with Potent Broad in Vitro and in Vivo Antimicrobial Activity (Chem. Eur. J. 49/2021)
R Ganesan, MA Dughbaj, L Ramirez, S Beringer, TL Aboye, A Shekhtman, ...
Chemistry–A European Journal 27 (49), 12450-12450, 2021
12021
Engineered cyclotides with potent broad antimicrobial activity
JC Palao, P Beringer, M Dughbaj, R Ganesan
US Patent App. 18/212,068, 2024
2024
Antimicrobial activity and action mechanism of chemokine CXCL14-derived antimicrobial peptide, CXCL14-C17 and its analogs
SS Yub, G Rajasekaran
JOURNAL OF PEPTIDE SCIENCE 24, S152-S153, 2018
2018
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