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Ruth Slack
Ruth Slack
Verified email at uottawa.ca - Homepage
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13125*2021
Role of AIF in caspase-dependent and caspase-independent cell death
SP Cregan, VL Dawson, RS Slack
Oncogene 23 (16), 2785-2796, 2004
6962004
Caspase 3 activity is required for skeletal muscle differentiation
P Fernando, JF Kelly, K Balazsi, RS Slack, LA Megeney
Proceedings of the National Academy of Sciences 99 (17), 11025-11030, 2002
6782002
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
SP Cregan, A Fortin, JG MacLaurin, SM Callaghan, F Cecconi, SW Yu, ...
The Journal of cell biology 158 (3), 507-517, 2002
5862002
Mitochondrial dynamics impacts stem cell identity and fate decisions by regulating a nuclear transcriptional program
M Khacho, A Clark, DS Svoboda, J Azzi, JG MacLaurin, C Meghaizel, ...
Cell stem cell 19 (2), 232-247, 2016
5632016
Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons
SP Cregan, JG MacLaurin, CG Craig, GS Robertson, DW Nicholson, ...
Journal of Neuroscience 19 (18), 7860-7869, 1999
4731999
Elevated mitochondrial bioenergetics and axonal arborization size are key contributors to the vulnerability of dopamine neurons
C Pacelli, N Giguère, MJ Bourque, M Lévesque, RS Slack, LÉ Trudeau
Current Biology 25 (18), 2349-2360, 2015
4652015
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ...
Human molecular genetics 19 (19), 3734-3746, 2010
4512010
OPA1‐dependent cristae modulation is essential for cellular adaptation to metabolic demand
DA Patten, J Wong, M Khacho, V Soubannier, RJ Mailloux, ...
The EMBO journal 33 (22), 2676-2691, 2014
3882014
Cyclin-dependent kinases as a therapeutic target for stroke
H Osuga, S Osuga, F Wang, R Fetni, MJ Hogan, RS Slack, AM Hakim, ...
Proceedings of the National Academy of Sciences 97 (18), 10254-10259, 2000
3702000
Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease
PD Smith, SJ Crocker, V Jackson-Lewis, KL Jordan-Sciutto, S Hayley, ...
Proceedings of the National Academy of Sciences 100 (23), 13650-13655, 2003
3622003
Involvement of interferon-γ in microglial-mediated loss of dopaminergic neurons
MP Mount, A Lira, D Grimes, PD Smith, S Faucher, R Slack, H Anisman, ...
Journal of Neuroscience 27 (12), 3328-3337, 2007
3462007
Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease
SJ Crocker, PD Smith, V Jackson-Lewis, WR Lamba, SP Hayley, E Grimm, ...
Journal of Neuroscience 23 (10), 4081-4091, 2003
3312003
Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma
D Chen, I Livne-bar, JL Vanderluit, RS Slack, M Agochiya, R Bremner
Cancer cell 5 (6), 539-551, 2004
3262004
Reactive oxygen species: stuck in the middle of neurodegeneration
DA Patten, M Germain, MA Kelly, RS Slack
Journal of Alzheimer's disease 20 (s2), S357-S367, 2010
3252010
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
ME Haque, KJ Thomas, C D'Souza, S Callaghan, T Kitada, RS Slack, ...
Proceedings of the National Academy of Sciences 105 (5), 1716-1721, 2008
3062008
Involvement of cell cycle elements, cyclin-dependent kinases, pRB, and E2F· DP, in B-amyloid-induced neuronal death
A Giovanni, F Wirtz-Brugger, E Keramaris, R Slack, DS Park
Journal of Biological Chemistry 274 (27), 19011-19016, 1999
2941999
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease
D Qu, J Rashidian, MP Mount, H Aleyasin, M Parsanejad, A Lira, E Haque, ...
Neuron 55 (1), 37-52, 2007
2792007
Mitochondria as central regulators of neural stem cell fate and cognitive function
M Khacho, R Harris, RS Slack
Nature Reviews Neuroscience 20 (1), 34-48, 2019
2772019
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death
A Fortin, SP Cregan, JG MacLaurin, N Kushwaha, ES Hickman, ...
The Journal of cell biology 155 (2), 207-216, 2001
2642001
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