Jacob S Yount
Jacob S Yount
Professor, Microbial Infection & Immunity, The Ohio State University
Verified email at
Cited by
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Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3
JS Yount, B Moltedo, YY Yang, G Charron, TM Moran, CB López, ...
Nature chemical biology 6 (8), 610-614, 2010
The tumour suppressor CYLD is a negative regulator of RIG‐I‐mediated antiviral response
CS Friedman, MA O'donnell, D Legarda‐Addison, A Ng, WB Cárdenas, ...
EMBO reports 9 (9), 930-936, 2008
Robust fluorescent detection of protein fatty-acylation with chemical reporters
G Charron, MM Zhang, JS Yount, J Wilson, AS Raghavan, E Shamir, ...
Journal of the American Chemical Society 131 (13), 4967-4975, 2009
S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus
JS Yount, RA Karssemeijer, HC Hang
Journal of Biological Chemistry 287 (23), 19631-19641, 2012
Opposing activities of IFITM proteins in SARS‐CoV‐2 infection
G Shi, AD Kenney, E Kudryashova, A Zani, L Zhang, KK Lai, ...
The EMBO journal 40 (3), e106501, 2021
Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation
A Percher, S Ramakrishnan, E Thinon, X Yuan, JS Yount, HC Hang
Proceedings of the National Academy of Sciences 113 (16), 4302-4307, 2016
MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering …
JS Yount, L Gitlin, TM Moran, CB López
The Journal of Immunology 180 (7), 4910-4918, 2008
Human genetic determinants of viral diseases
AD Kenney, JA Dowdle, L Bozzacco, TM McMichael, C St. Gelais, ...
Annual review of genetics 51 (1), 241-263, 2017
Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination
NM Chesarino, TM McMichael, JC Hach, JS Yount
Journal of Biological Chemistry 289 (17), 11986-11992, 2014
A novel role for viral-defective interfering particles in enhancing dendritic cell maturation
JS Yount, TA Kraus, CM Horvath, TM Moran, CB López
The Journal of Immunology 177 (7), 4503-4513, 2006
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways
S Chen, S Bonifati, Z Qin, C St. Gelais, KM Kodigepalli, BS Barrett, ...
Proceedings of the National Academy of Sciences 115 (16), E3798-E3807, 2018
Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection
B Moltedo, W Li, JS Yount, TM Moran
PLoS pathogens 7 (11), e1002345, 2011
E3 ubiquitin ligase NEDD4 promotes influenza virus infection by decreasing levels of the antiviral protein IFITM3
NM Chesarino, TM McMichael, JS Yount
PLoS pathogens 11 (8), e1005095, 2015
Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1
C St. Gelais, S de Silva, JC Hach, TE White, F Diaz-Griffero, JS Yount, ...
Journal of virology 88 (10), 5834-5844, 2014
IFITM 3 requires an amphipathic helix for antiviral activity
NM Chesarino, AA Compton, TM McMichael, AD Kenney, L Zhang, ...
EMBO reports 18 (10), 1740-1751, 2017
Antibacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates
LK Tsou, M Lara-Tejero, J RoseFigura, ZJ Zhang, YC Wang, JS Yount, ...
Journal of the American Chemical Society 138 (7), 2209-2218, 2016
Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors
C Zeng, JP Evans, R Pearson, P Qu, YM Zheng, RT Robinson, ...
JCI insight 5 (22), 2020
From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections
M Chemudupati, AD Kenney, S Bonifati, A Zani, TM McMichael, L Wu, ...
Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1866 (3), 382-394, 2019
Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity
AA Compton, N Roy, F Porrot, A Billet, N Casartelli, JS Yount, C Liang, ...
EMBO reports 17 (11), 1657-1671, 2016
SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity
JM Antonucci, C St. Gelais, S De Silva, JS Yount, C Tang, X Ji, C Shepard, ...
Nature medicine 22 (10), 1072-1074, 2016
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