| Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes S Yeoh, RA O'Donnell, K Koussis, AR Dluzewski, KH Ansell, SA Osborne, ... Cell 131 (6), 1072-1083, 2007 | 400 | 2007 |
| A multifunctional serine protease primes the malaria parasite for red blood cell invasion K Koussis, C Withers‐Martinez, S Yeoh, M Child, F Hackett, E Knuepfer, ... The EMBO journal 28 (6), 725-735, 2009 | 213 | 2009 |
| Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents KE Tsitsanou, T Thireou, CE Drakou, K Koussis, MV Keramioti, ... Cellular and Molecular Life Sciences 69, 283-297, 2012 | 123 | 2012 |
| Global Identification of Multiple Substrates for Plasmodium falciparum SUB1, an Essential Malarial Processing Protease NC Silmon de Monerri, HR Flynn, MG Campos, F Hackett, K Koussis, ... Infection and immunity 79 (3), 1086-1097, 2011 | 120 | 2011 |
| Roles of Proteases during Invasion and Egress by Plasmodium and Toxoplasma TJ Dowse, K Koussis, MJ Blackman, D Soldati-Favre Molecular Mechanisms of Parasite Invasion: Subcellular Biochemistry, 121-139, 2008 | 77 | 2008 |
| Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target C Withers-Martinez, C Suarez, S Fulle, S Kher, M Penzo, JP Ebejer, ... International Journal for Parasitology 42 (6), 597-612, 2012 | 62 | 2012 |
| Inhibition of Anopheles gambiae odorant receptor function by mosquito repellents P Tsitoura, K Koussis, K Iatrou Journal of Biological Chemistry 290 (12), 7961-7972, 2015 | 38 | 2015 |
| Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking T Thireou, G Kythreoti, KE Tsitsanou, K Koussis, CE Drakou, J Kinnersley, ... Insect biochemistry and molecular biology 98, 48-61, 2018 | 36 | 2018 |
| Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG AC Balestra, K Koussis, N Klages, SA Howell, HR Flynn, M Bantscheff, ... Science advances 7 (13), eabe5396, 2021 | 34 | 2021 |
| Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function K Koussis, C Withers-Martinez, DA Baker, MJ Blackman Life science alliance 3 (4), 2020 | 29 | 2020 |
| Odorant-binding protein-based identification of natural spatial repellents for the African malaria mosquito Anopheles gambiae T Kröber, K Koussis, M Bourquin, P Tsitoura, M Konstantopoulou, ... Insect biochemistry and molecular biology 96, 36-50, 2018 | 27 | 2018 |
| Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1 E Lidumniece, C Withers-Martinez, F Hackett, CR Collins, AJ Perrin, ... Proceedings of the National Academy of Sciences 118 (20), e2022696118, 2021 | 14 | 2021 |
| Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor MSY Tan, K Koussis, C Withers‐Martinez, SA Howell, JA Thomas, ... The EMBO journal 40 (11), e107226, 2021 | 11 | 2021 |
| A malaria parasite phospholipase facilitates efficient asexual blood stage egress A Ramaprasad, PC Burda, K Koussis, JA Thomas, E Pietsch, E Calvani, ... PLoS pathogens 19 (6), e1011449, 2023 | 8 | 2023 |
| Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host K Koussis, E Goulielmaki, A Chalari, C Withers-Martinez, I Siden-Kiamos, ... PLoS One 12 (1), e0170260, 2017 | 7 | 2017 |
| A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1 SJ Tarr, C Withers-Martinez, HR Flynn, AP Snijders, L Masino, K Koussis, ... Biochemical Journal 477 (2), 525-540, 2020 | 6 | 2020 |
| Distinct effects of HIV protease inhibitors and ERAD inhibitors on zygote to ookinete transition of the malaria parasite E Goulielmaki, S Kaforou, K Venugopal, TG Loukeris, I Siden-Kiamos, ... Molecular and Biochemical Parasitology 220, 10-14, 2018 | 5 | 2018 |
| Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium Z Tampaki, RS Mwakubambanya, E Goulielmaki, S Kaforou, K Kim, ... PloS one 10 (3), e0121379, 2015 | 4 | 2015 |
| A multipass membrane protein interacts with the cGMP-dependent protein kinase to regulate critical calcium signals in malaria parasites AC Balestra, K Koussis, N Klages, SA Howell, HR Flynn, M Bantscheff, ... BioRxiv, 2020.07. 18.209973, 2020 | 2 | 2020 |
| Functional dissection of a malarial serine protease K Koussis PQDT-Global, 2008 | 1 | 2008 |
Inga Siden-KiamosInstitute of Molecular Biology and Biotechnology, FORTHVerified email at imbb.forth.gr
