MST4 phosphorylation of ATG4B regulates autophagic activity, tumorigenicity, and radioresistance in glioblastoma T Huang, CK Kim, AA Alvarez, RP Pangeni, X Wan, X Song, T Shi, Y Yang, ... Cancer cell 32 (6), 840-855. e8, 2017 | 198 | 2017 |
The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain RP Pangeni, P Channathodiyil, DS Huen, LW Eagles, BK Johal, D Pasha, ... Clinical epigenetics 7, 1-17, 2015 | 104 | 2015 |
A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways T Huang, AA Alvarez, RP Pangeni, CM Horbinski, S Lu, SH Kim, ... Nature communications 7 (1), 1-16, 2016 | 85 | 2016 |
Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer K Zhang, J Wang, L Yang, YC Yuan, TR Tong, J Wu, X Yun, M Bonner, ... Molecular cancer 17, 1-15, 2018 | 71 | 2018 |
Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer K Zhang, L Yang, J Wang, T Sun, Y Guo, R Nelson, TR Tong, R Pangeni, ... Cell Communication and Signaling 17, 1-17, 2019 | 45 | 2019 |
Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma RP Pangeni, Z Zhang, AA Alvarez, X Wan, N Sastry, S Lu, T Shi, T Huang, ... Epigenetics 13 (4), 432-448, 2018 | 34 | 2018 |
G9a regulates tumorigenicity and stemness through genome-wide DNA methylation reprogramming in non-small cell lung cancer RP Pangeni, L Yang, K Zhang, J Wang, W Li, C Guo, X Yun, T Sun, ... Clinical epigenetics 12, 1-17, 2020 | 31 | 2020 |
Targeting USP22 suppresses tumorigenicity and enhances cisplatin sensitivity through ALDH1A3 downregulation in cancer-initiating cells from lung adenocarcinoma X Yun, K Zhang, J Wang, RP Pangeni, L Yang, M Bonner, J Wu, J Wang, ... Molecular Cancer Research 16 (7), 1161-1171, 2018 | 31 | 2018 |
The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors I Topchu, RP Pangeni, I Bychkov, SA Miller, E Izumchenko, J Yu, ... Cellular and Molecular Life Sciences 79 (6), 285, 2022 | 25 | 2022 |
G9a promotes invasion and metastasis of non–small cell lung cancer through enhancing focal adhesion kinase activation via NF-κB signaling pathway T Sun, K Zhang, RP Pangeni, J Wu, W Li, Y Du, Y Guo, S Chaurasiya, ... Molecular Cancer Research 19 (3), 429-440, 2021 | 21 | 2021 |
LY6K promotes glioblastoma tumorigenicity via CAV-1–mediated ERK1/2 signaling enhancement NG Sastry, X Wan, T Huang, AA Alvarez, RP Pangeni, X Song, CD James, ... Neuro-oncology 22 (9), 1315-1326, 2020 | 20 | 2020 |
Cetuximab-triptolide conjugate suppresses the growth of EGFR-overexpressing lung cancers through targeting RNA polymerase II K Zhang, Y Ma, Y Guo, T Sun, J Wu, RP Pangeni, M Lin, W Li, D Horne, ... Molecular Therapy-Oncolytics 18, 304-316, 2020 | 14 | 2020 |
COVID-19 and Long COVID: Disruption of the Neurovascular Unit, Blood-Brain Barrier, and Tight Junctions D Kempuraj, KK Aenlle, J Cohen, A Mathew, D Isler, RP Pangeni, ... The Neuroscientist, 10738584231194927, 2023 | 8 | 2023 |
Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression T Sun, K Zhang, W Li, Y Liu, RP Pangeni, A Li, L Arvanitis, DJ Raz Cell Communication and Signaling 20 (1), 147, 2022 | 7 | 2022 |
Genome-wide methylation analyses identifies non-coding RNA genes dysregulated in breast tumours that metastasise to the brain RP Pangeni, I Olivaries, D Huen, VC Buzatto, TP Dawson, KM Ashton, ... Scientific Reports 12 (1), 1102, 2022 | 5 | 2022 |
A Non-genetic Mechanism for Chemoresistance in Lung Cancer: The Role of Integrin β4/Paxillin Axis A Mohanty, A Nam, A Pozhitkov, S Bhattacharya, L Yang, A Nathan, X Wu, ... bioRxiv, 781807, 2019 | 5 | 2019 |
J Raizer, J.; A Kessler, J.; Brenann, CW; et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways T Huang, AA Alvarez, RP Pangeni, CM Horbinski, S Lu, SH Kim, ... Nat. Commun 7, 12885, 2016 | 5 | 2016 |
CSIG-08. A REGULATORY CIRCUIT OF miR-125b/miR-20b AND Wnt SIGNALING CONTROLS GBM PHENOTYPES THROUGH FZD6-MEDIATED PATHWAYS T Huang, A Alvarez, R Pangeni, C Horbinski, S Lu, CD James, J Raizer, ... Neuro-Oncology 18 (suppl_6), vi42-vi42, 2016 | 2 | 2016 |
Histone Methyltransferase G9a Promotes Invasion of Non-small Cell Lung Cancer Through Enhancing Focaladhesionkinase Activationvia NF-KB Signaling Pathway T Sun, K Zhang, RP Pangeni, W Li, Y Du, S Chaurasiya, L Arvanitis, ... | 1 | 2020 |
BM-24 MULTI-GENE METHYLATION ANALYSIS TO IDENTIFY SIGNATURE GENES FOR BRAIN METASTASIS FROM PRIMARY BREAST TUMORS RP Pangeni, D Huen, K Ashton, C Walker, TP Dawson, C Davis, F Latif, ... Neuro-Oncology 16 (suppl_5), v37-v37, 2014 | 1 | 2014 |