Zbynek Prokop
Zbynek Prokop
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Strategies for stabilization of enzymes in organic solvents
V Stepankova, S Bidmanova, T Koudelakova, Z Prokop, R Chaloupkova, ...
Acs Catalysis 3 (12), 2823-2836, 2013
Machine learning in enzyme engineering
S Mazurenko, Z Prokop, J Damborsky
ACS Catalysis 10 (2), 1210-1223, 2019
Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate
M Pavlova, M Klvana, Z Prokop, R Chaloupkova, P Banas, M Otyepka, ...
Nature chemical biology 5 (10), 727-733, 2009
Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway
P Dvorak, L Chrast, PI Nikel, R Fedr, K Soucek, M Sedlackova, ...
Microbial cell factories 14, 1-15, 2015
Modification of activity and specificity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 by engineering of its entrance tunnel
R Chaloupková, J Sýkorová, Z Prokop, A Jesenská, M Monincová, ...
Journal of Biological Chemistry 278 (52), 52622-52628, 2003
Haloalkane dehalogenases: biotechnological applications
T Koudelakova, S Bidmanova, P Dvorak, A Pavelka, R Chaloupkova, ...
Biotechnology journal 8 (1), 32-45, 2013
FireProt: energy-and evolution-based computational design of thermostable multiple-point mutants
D Bednar, K Beerens, E Sebestova, J Bendl, S Khare, R Chaloupkova, ...
PLoS computational biology 11 (11), e1004556, 2015
Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel
T Koudelakova, R Chaloupkova, J Brezovsky, Z Prokop, E Sebestova, ...
Angewandte Chemie 125 (7), 2013-2017, 2013
Engineering enzyme access tunnels
P Kokkonen, D Bednar, G Pinto, Z Prokop, J Damborsky
Biotechnology advances 37 (6), 107386, 2019
FireProt: web server for automated design of thermostable proteins
M Musil, J Stourac, J Bendl, J Brezovsky, Z Prokop, J Zendulka, ...
Nucleic acids research 45 (W1), W393-W399, 2017
Mobility, bioavailability, and toxic effects of cadmium in soil samples
Z Prokop, P Cupr, V Zlevorova-Zlamalikova, J Komárek, L Dusek, ...
Environmental Research 91 (2), 119-126, 2003
Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering
Z Prokop, Y Sato, J Brezovsky, T Mozga, R Chaloupkova, T Koudelakova, ...
Angewandte Chemie International Edition 49 (35), 6111-6115, 2010
Catalytic mechanism of the haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26
Z Prokop, M Monincová, R Chaloupková, M Klvanˇa, Y Nagata, ...
Journal of Biological Chemistry 278 (46), 45094-45100, 2003
Pathways and mechanisms for product release in the engineered haloalkane dehalogenases explored using classical and random acceleration molecular dynamics simulations
M Klvana, M Pavlova, T Koudelakova, R Chaloupkova, P Dvorak, ...
Journal of molecular biology 392 (5), 1339-1356, 2009
Enzymes fight chemical weapons
Z Prokop, F Opluštil, J DeFrank, J Damborský
Biotechnology Journal: Healthcare Nutrition Technology 1 (12), 1370-1380, 2006
Two Rhizobial Strains, Mesorhizobium loti MAFF303099 and Bradyrhizobium japonicum USDA110, Encode Haloalkane Dehalogenases with Novel Structures …
Y Sato, M Monincová, R Chaloupková, Z Prokop, Y Ohtsubo, ...
Applied and environmental microbiology 71 (8), 4372-4379, 2005
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis
M Bohác, Y Nagata, Z Prokop, M Prokop, M Monincová, M Tsuda, J Koca, ...
Biochemistry 41 (48), 14272-14280, 2002
Engineering a de novo transport tunnel
J Brezovsky, P Babkova, O Degtjarik, A Fortova, A Gora, I Iermak, ...
ACS Catalysis 6 (11), 7597-7610, 2016
Degradation of β-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26
Y Nagata, Z Prokop, Y Sato, P Jerabek, A Kumar, Y Ohtsubo, M Tsuda, ...
Applied and environmental microbiology 71 (4), 2183-2185, 2005
A single mutation in a tunnel to the active site changes the mechanism and kinetics of product release in haloalkane dehalogenase LinB
L Biedermannová, Z Prokop, A Gora, E Chovancová, M Kovács, ...
Journal of Biological Chemistry 287 (34), 29062-29074, 2012
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