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Brooke Fiala
Brooke Fiala
Research Scientist/Engineer III, Institute for Protein Design, University of Washington
Verified email at uw.edu - Homepage
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Cited by
Cited by
Year
Functional SARS-CoV-2-specific immune memory persists after mild COVID-19
LB Rodda, J Netland, L Shehata, KB Pruner, PA Morawski, CD Thouvenel, ...
Cell 184 (1), 169-183. e17, 2021
5492021
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2
AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, ...
Cell 183 (5), 1367-1382. e17, 2020
2832020
Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection
KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, ...
The Journal of infectious diseases 223 (2), 197-205, 2021
2362021
Induction of potent neutralizing antibody responses by a designed protein nanoparticle vaccine for respiratory syncytial virus
J Marcandalli, B Fiala, S Ols, M Perotti, W de van der Schueren, J Snijder, ...
Cell 176 (6), 1420-1431. e17, 2019
2362019
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
PS Arunachalam, AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, ...
Nature 594 (7862), 253-258, 2021
1422021
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
PJM Brouwer, A Antanasijevic, Z Berndsen, A Yasmeen, B Fiala, TPL Bijl, ...
Nature Communications 10 (1), 1-17, 2019
972019
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ...
Cell 184 (21), 5432-5447. e16, 2021
712021
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice
NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ...
Proceedings of the National Academy of Sciences 118 (38), e2106845118, 2021
302021
Discovery and engineering of enhanced SUMO protease enzymes
YTK Lau, V Baytshtok, TA Howard, BM Fiala, JLM Johnson, LP Carter, ...
Journal of Biological Chemistry 293 (34), 13224-13233, 2018
242018
Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates
PS Arunachalam, AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, ...
bioRxiv, 2021
202021
Stabilization of the SARS-CoV-2 spike receptor-binding domain using deep mutational scanning and structure-based design
D Ellis, N Brunette, KHD Crawford, AC Walls, MN Pham, C Chen, ...
Frontiers in immunology 12, 710263, 2021
172021
Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection (medRxiv)
KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, ...
Published online August 7, 2020.08, 2020
62020
Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice
AC Walls, LA VanBlargan, K Wu, A Choi, MJ Navarro, D Lee, L Avena, ...
Cell reports 40 (9), 111299, 2022
22022
Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
H Malhi, LJ Homad, YH Wan, B Poudel, B Fiala, AJ Borst, JY Wang, ...
Cell Reports Medicine 3 (6), 100658, 2022
22022
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine
PS Arunachalam, Y Feng, U Ashraf, M Hu, AC Walls, VV Edara, ...
Science Translational Medicine 14 (658), eabq4130, 2022
12022
Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice
L Grigoryan, A Lee, AC Walls, L Lai, B Franco, PS Arunachalam, Y Feng, ...
NPJ vaccines 7 (1), 1-14, 2022
12022
Antigen-and scaffold-specific antibody responses to protein nanoparticle immunogens
JC Kraft, MN Pham, L Shehata, M Brinkkemper, S Boyoglu-Barnum, ...
Cell Reports Medicine, 100780, 2022
2022
Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region
CT Schoeder, P Gilchuk, AK Sangha, KV Ledwitch, DC Malherbe, ...
PLoS pathogens 18 (5), e1010518, 2022
2022
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
JY Wang, A Khmelinskaia, W Sheffler, MC Miranda, A Antanasijevic, ...
bioRxiv, 2022
2022
Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.
AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, MJ Navarro, L Lai, ...
Biorxiv: the Preprint Server for Biology, 2021
2021
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